New Methods to Study Adult Neurogenesis and Progenitor Maturation
Neuronal progenitors are faced with many forks on the road to becoming one of more than 1,000 different neurons found in the human central nervous system...
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Dampening Down Neurotransmission to Sharpen Vision in Aging Monkeys?
Counterintuitive as it may seem, in tomorrow's Science researchers report that the inhibitory neurotransmitter ã-aminobutyric acid (GABA) can temporarily restore age-related losses of visual acuity in monkeys...
Diagnosis of AD—Does Spinal Fluid Hold the Key?
In this week's Journal of the American Medical Association, researchers report a correlation between Alzheimer's disease (AD) and the appearance in the cerebrospinal fluid (CSF) of two proteins thought to play major roles in the progression of the disease—amyloid β42 (Aβ42) and tau...
Statins Reduce Brain Cholesterol Metabolite
Several anticholesterol drugs, particularly statins, at standard doses can significantly reduce plasma levels of the brain cholesterol degradation product 24S-hydrocholesterol, according to a report in this week's Archives of Neurology...
Alzheimer's Medal Goes to Pioneer in Diffusible Aβ
Massimo Tabaton of the University of Genoa, Italy, has been awarded this year's Alzheimer's Medal, presented annually by the associate editors of the Journal of Alzheimer's Disease "for the best article published in the previous year's volume."...
Tau and α-synuclein at the Nexus of Alzheimer's and Parkinson's
There is growing interest in the overlap among Alzheimer's disease, Parkinson's disease, and less common synucleinopathies and tauopathies that can share features of both diseases...
Amyloid Oligomer Antibody—One Size Fits All?
Like good cholesterol and bad cholesterol, the Alzheimer's community has realized that there may also be good Aβ and bad Aβ...
Adult Stem Cells Target Inflammation, Replace Cells in MS Model
Stem cells injected into the cerebral ventricles—or even injected intravenously—find their way to sites of inflammation in an animal model of multiple sclerosis (MS), according to a report in today’s Nature...
AD Cell Cycle Reentry—Early Rather Than Late
What happens when the protein machinery that drives the cell division cycle gets activated in non-dividing cells such as neurons? The cells will most likely die. Recent evidence suggests that just this type of scenario plays out in the brains of Alzheimer's patients...
Genes and Longevity—Can One Base Pair Make a Difference?
In this month's Journal of Medical Genetics, a group of Italian researchers propose that there is a link between longevity and a single nucleotide polymorphism (SNP) in the promoter for the antiinflammatory cytokine interleukin-10 (IL-10)...
International Titisee Conference 2003
Philipp Kahle and Bart De Strooper Report from Lake Titisee, Germany: Part I Philipp Kahle and Bart De Strooper Report from Lake Titisee, Germany: Part II Philipp Kahle and Bart De Strooper Report from Lake Titisee, Germany: Part III International Titisee
Philipp Kahle and Bart De Strooper Report from Lake Titisee, Germany: Part III
Read Part III of Philip Kahle’s and Bart de Strooper’s report from the 87th International Titisee Conference in Germany...
Philipp Kahle and Bart De Strooper Report from Lake Titisee, Germany: Part I
Almost exactly 100 years after Alois Alzheimer saw his first patient who complained about "having lost herself," <strong>Christian Haass</strong> and <strong>Roger Nitsch</strong> invited a panel of international opinion leaders to gather in the German Black Forest...
Philipp Kahle and Bart De Strooper Report from Lake Titisee, Germany: Part II
Read Part II of Philip Kahle’s and Bart de Strooper’s report from the 87th International Titisee Conference in Germany...
Annotation of Human Chromosome 7 Reaches Breakpoint
In yesterday’s Sciencexpress, researchers described the most complete annotation of human chromosome 7 to date. Capitalizing on the availability of clinical and medical information from a variety of databases...
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