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A contentious hypothesis about where and how Parkinson’s disease starts off is gaining ground as new studies provide clues in its support. Neuroanatomists Heiko Braak and Kelly Del Tredici, both at the University of Ulm in Germany, have described the dist
Could PD start in the belly and spread from there, along paths laid out by neurons, to successive areas of the brain in a predictable sequence?...
A research consortium is gearing up to conduct a multicenter Phase 3 clinical trial of the blood pressure medication nilvadipine in AD patients...
Just as jammed highways can shut down cities, disrupted intracellular trafficking along axons can trigger neuronal death and neurodegenerative disease...
When neuroanatomists proposed a new theory on the origin and progression of Parkinson’s disease, they started a debate in the field...
Uppsala: Conference Puts Uppsala on Immunotherapy Map Uppsala: Is Tau Immunotherapy Taking Off? Uppsala: Immunotherapy—Not Just for AD Anymore Science has come a long way since botanist Carl Linnaeus built his catalogue and plant extracts were the medicin
As immune-based therapies targeting Aβ and tau are beginning to show promise for the treatment of Alzheimer’s, what about other disorders of the nervous system?...
Effective cell replacement therapy for Parkinson’s disease has been an elusive target...
Sometimes a fresh pair of eyes can see new pathways to solve a problem...
When an anatomist first proposed that Parkinson’s disease begins in the gut, then slowly makes its way to the brain, his idea might have sounded like fiction...
Researchers showed that memory consolidation in the cortex can occur within 48 hours if the new information fits into an existing mental schema...
Pericyte-enwrapping blood vessels near a spinal lesion will differentiate and move toward the injury, forming the core of an astrocyte-coated scar...
New research points to two potential approaches for attacking PD—one going after a well-known culprit, the other targeting an up-and-coming one...
A paper in today’s Nature Neuroscience contends that Aβ43 can play a major role in pathology...
Genetics may play a bigger role in Parkinson's disease than previously appreciated...
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