The Microbiome and Disease—What Does Poop Have to Do With It?
Simple lifestyle factors such as alcohol consumption and stool quality alter gut flora. Research on the microbiome and disease should account for those factors, a study reports.
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α-Synuclein Spurs Neuroinflammation Via Microglial LRRK2
The transcription factor NFATc2 mediates this response.
Alzheimer's Risk Genes Nip at Hippocampus Throughout Life
ApoE4 does so much more strongly than the other known genes collected in a polygenic risk score.
Epigenomic Roadmap Points to Causal Genes
By looking for SNPs that affect how transcription factors bind DNA, researchers nominated causal genes for 30 Alzheimer’s and Parkinson’s GWAS hits.
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