CRISPR Gene Editing May Not Be so Precise After All
Researchers found large deletions, inversions, or insertions in about one-fifth of edited cells, suggesting caution for therapeutic uses of the technology.
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Researchers found large deletions, inversions, or insertions in about one-fifth of edited cells, suggesting caution for therapeutic uses of the technology.
Blood from an old mouse ages the brain of a young one, but how? Researchers report that VCAM1 on brain endothelial cells facilitates the process.
At Keystone, researchers placed pathological tau on both sides of the synaptic cleft, along with complement proteins. Activated microglia gobbled up tau-laden neurons, and even may have facilitated tau’s spread in the brain.