Exosomes and Antibodies Tie Plasma Aβ and Tau to Alzheimer’s
Researchers at SfN 2016 reported that oligomeric and exosomal forms in plasma predict AD as early as a decade prior to symptoms.
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Researchers at SfN 2016 reported that oligomeric and exosomal forms in plasma predict AD as early as a decade prior to symptoms.
Where does TREM2-dependent microglial activity fit into the staging diagram of Alzheimer’s disease?
Despite conflicting results in the past, a large new study analyzing multiple statins in different ethnic groups suggests a protective effect from this class of medication.
Starting next month, Bart de Strooper will head national institute focusing on mechanistic research and evidence-based care.
Researchers at SfN 2016 proposed dialing up the immune response in Alzheimer’s brains to enhance phagocytosis.
At SfN 2016, researchers debuted new mouse models that may better represent human disease.
Researchers at SfN 2016 touted the advantages of APP knock-ins, but noted they are less useful than overexpression models for studying behavior.
Astrocytes and Exosomes Implicated in Protein Propagation Knock-In Alzheimer’s Mice Catch on More Broadly in the Field Next-Generation Mouse Models: Tau Knock-ins and Human Chimeras Inflammation Helps Microglia Clear Amyloid from AD Brains Exosomes and An
Cell lines can serve as sensors for strains found in different human tauopathies.
Researchers at SfN 2016 painted a more detailed picture of how misfolded proteins may proliferate, as one cell spreads these “hot potatoes” to the next.
Diminishing Alzheimer’s pathology in mice appears to be as easy as shining a light in their eyes. Could it work in people?