Clinical Trials Roundup: Broadening the Lines of Attack
Speakers at Alzheimer’s conference reviewed planned Phase 1 and prevention trials and preclinical studies.
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Speakers at Alzheimer’s conference reviewed planned Phase 1 and prevention trials and preclinical studies.
Hunting for rare mutations that cause dementia, researchers have spotted, but not yet snagged, some tantalizing candidates.
The May 26 Nature Neuroscience online debuts 25 new candidate genes for amyotrophic lateral sclerosis...
A parkinsonism-associated ubiquitin ligase interacts with parkin to promote mitophagy.
Rare variants of AD share some common areas of brain atrophy, but are also unique by way of degeneration in specific functional networks that correspond with clinical symptoms.
Anticipating future clinical trials for Huntington’s disease, researchers are seeking sensitive measures that will predict onset and track progression...
Brain connections weaken years before cognition in sporadic and familial Alzheimer’s.
Preliminary data from Parkinson’s Progression Markers Initiative suggests that cerebrospinal fluid biomarkers distinguish the most rapidly progressing form of Parkinson’s.
Before cognition falters, Alzheimer’s disease wreaks havoc on synapses, the brain’s subcellular communication hubs.
Brain imaging distinguishes ALS patients with C9ORF72 expansions from those with other forms of the disease.
As β-secretase inhibitors head into Alzheimer’s disease trials, researchers are paying close attention to what else BACE1 does besides snip amyloid-β from APP...
At a San Francisco conference addressing Alzheimer’s and related disorders, the agenda featured a diverse mix of topics—occasionally even from the same lab...
Today, the MetLife Foundation honored Yueming Li and Lennart Mucke with its 2013 Awards for Medical Research in Alzheimer’s Disease...
Two new papers this month shore up the connection between cell waste disposal and function of neurons...
Results of a two-year clinical trial suggest that a mixture of B vitamins slows atrophy up to sevenfold in areas of the brain that are vulnerable to degeneration in AD...