Microglia Activation—Venusberg Meeting Questions M1, M2 Designations Inflammatory Crosstalk Between Periphery and Brain Blessing or Curse? Peripheral Cytokines in the Brain Glial Imaging—Amid Slow Progress, EU Project Takes Up Challenge Venusberg Meeting
Some dismiss it as a therapeutic dead end, but for others, the M1 muscarinic receptor is a target for ongoing drug development research in Alzheimer’s disease...
Pyroglutamate Aβ is a particularly toxic version of the peptide at the center of AD pathogenesis; in fact, some scientists claim it seeds the formation of plaques...
Tau, α-Synuclein Spread: Crazy Stuff—How Might It Work? Like Star Born of Supernova, Plaque Born of Exploded Neuron? Can Dousing PyroGlu-Aβ Treat Alzheimer’s Disease? Field Ramps Up "Mini" Mouse MRI LRRK Watchers’ Eyes Turn to Inflammation, Auto
Many researchers believe that neurodegeneration's takeover of one's brain might be driven by pathogenic, misfolded proteins spreading through interconnected neural networks...
Growing evidence suggests that neurons begin faltering decades before cognitive symptoms in AD, but identifying the molecular culprits at play has proven challenging...