Oligodendrocyte Support System Fails Early in ALS
Oligodendrocytes are joining astrocytes and microglia as members of a glial syndicate involved in the pathology of amyotrophic lateral sclerosis...
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Longitudinal Data Stand Out at AD/PD Imaging Satellite
The 11th AD/PD Conference hosted a day-long exchange of new imaging data and discussion of current challenges for the research community in these two disorders...
American Academy of Neurology: 2013 Annual Meeting
Quick-and-Early IVIG Therapy: Hints of Promise? Anti-Amyloid Results Show Modest Benefits, Mild Side Effects Wrapping Up Enrollment, ADNI 2, PPMI Focus on Earlier Disease Drug Data Dash at AAN Annual Conference The ANN conference in San Diego covered such
Drug Data Dash at AAN Annual Conference
There were so many new data on neurodegenerative disease trials at the recent AAN meeting that organizers crammed some of them into a session of three-minute talks...
Sleep Patterns, Circadian Clock Linked to Aβ Oxidative Stress
Disrupted sleep-wake cycles often accompany neurodegeneration, but scientists are unsure why...
From Natural History, A "Renaissance" for Amyloid Hypothesis
Scientists quipped about Florence as a fitting setting for what they perceive to be a resurgence of the amyloid hypothesis after a beleaguered period of setbacks...
Wrapping Up Enrollment, ADNI 2, PPMI Focus on Earlier Disease
The Alzheimer’s Disease Neuroimaging Initiative steering committee gathered to exchange the latest developments in ADNI 2...
Anti-Amyloid Results Show Modest Benefits, Mild Side Effects
Scientists continue to squeeze every last bit of information out of Phase 3 trials for anti-amyloid antibodies solanezumab and bapineuzumab...
Experimental AD Vaccine Hitches a Ride on Tetanus Toxin
A new AD vaccine co-opts memory T helper cells to cajole B cells into producing anti-Aβ antibodies...
FDA Invites Comment on Drug Testing Guidance for Early AD
Scientists have turned their attention toward testing therapies in early-stage patients who have underlying brain pathology but little to no functional impairment...
Quick-and-Early IVIG Therapy: Hints of Promise?
If another small, hopeful trial is to be believed, pooled antibody treatment has the potential to stave off dementia...
In Pursuit of Toxic Tau
Neurofibrillary tangles of tau protein litter Alzheimer’s disease brains, but are they actually bad for neurons?...
Aβ, Neural Activity Linked to DNA Damage
DNA damage accrues in Alzheimer's disease and in the aging brain, but would anyone have predicted that neural activity is to blame?...
BACE Inhibitors Barrel Forward—Next Hurdles: Safety, Efficacy
After more than a decade of seemingly pushing against a wall, BACE inhibitors for Alzheimer’s disease are finally surging forward...
Dementia in Movement Disorders: What Causes It?
Adding insult to injury, many patients with a movement disorder get dementia, too...
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