Tau Tracers Shine at Boston Conference
Tau ligands for PET scans were among the hot topics at the Alzheimer’s Association International Conference in Boston.
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Tau ligands for PET scans were among the hot topics at the Alzheimer’s Association International Conference in Boston.
Studies reported at AAIC demonstrate that biomarkers help predict who will develop cognitive impairment and dementia.
Motor and cortical neurons are particularly vulnerable to FUSopathy. A new paper suggests they fail because they depend strongly on FUS to regulate transcription.
Researchers identified a genetic variant in the microglial gene CD33 that protects against Alzheimer’s.
Alzheimer’s and prion disease may be linked through an α-secretase.
The route to early dementia starts in adolescence, with low cognitive function and alcohol intoxication as major predictors.
Expansions in ataxin-2 can lead to either ALS or spinocerebellar ataxia—even in the same family, according to a new pedigree from New York.
Two studies examine factors that heighten the risk for dementia in type 2 diabetes patients. Both highlight depression as a dangerous comorbidity.
A stem cell-derived structure mimics crucial features of human brain development and could aid studies in schizophrenia, autism, maybe neurodegeneration.
Functional genomics and mouse analyses blame waning levels of histone-binding protein for memory loss in aging.
Researchers say that analyzing long stretches of homozygosity in people of Caribbean Hispanic descent represents an approach to finding rare, recessive Alzheimer’s mutations.
In sporadic and familial Parkinson's, faulty parkin may damage dopamine neurons by letting a deadly protein linger.
Researchers nabbed rare variants in Alzheimer’s genes by sequencing DNA from people with very high or very low levels of cerebrospinal fluid biomarkers.
Fueling (or rekindling) controversy over anti-aging benefits of sirtuins, researchers report that Sirt1 lengthens lifespan in mice.
Without the protein beclin 1, rapacious microglia choke on amyloid β.