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A Role for a Synuclein Protein

Synucleins are small cytoplasmic proteins that are found in synaptic terminals. They are present in senile plaques and Lewy bodies (features of Alzheimer's disease and familial Parkinson's disease)...

Success with Artificial Chromosomes

(From Nature Biotechnology press release.) Each cell in our bodies contains 46 chromosomes. But one day far in the future, doctors may give us an extra miniature chromosome containing therapeutic genes to treat disease...

Transgenic Mouse Mill

Breeding “knockout” mice is a prized tool for evaluating the function of genes, but it is a ponderous and costly tool, consuming many months and thousands of dollars to create each new knockout strain...

New Parkinson’s Gene

A gene on the long arm of chromosome 6 has been linked to an inherited form of Parkinson’s disease, called autosomal recessive juvenile parkinsonism (AR-JP)...

New Alzheimer's Journal

Scientists often complain that scientific journals take too long to review manuscripts, and that subscription prices are unaffordable. A new journal devoted to Alzheimer's disease research, Alzheimer's Reports...

Caspase's Role in Apoptosis Clarified

Two recent papers describe the processes involved in the final stages of apoptotic cell death. During apoptosis, enzymes known as caspases break down cellular proteins, causing severe morphological changes and cell shrinkage...

Entire Genome Yields to a Chip

Researchers at California-based Affymetrix have analyzed the activity of every gene in the yeast genome in a single experiment using a new "DNA chip." This remarkable technological feat hints of a future...

TGF-β1 Linked to Plaque Formation

A history of brain injury raises a person’s risk of Alzheimer’s disease, and many researchers now suspect that the brain’s inflammatory responses to injury may magnify the neurodegenerative process...

MEDLINE Now Free to the Public

The National Library of Medicine's MEDLINE database is now accessible free to the general public through PubMed and Internet Grateful Med. Hot links to IGM and PubMed are available on the NLM home page...

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