Paper Alert: Mass Spec of Tau Points to Ubiquitination
A study first summarized in our SfN conference news, on post-translational modifications of the protein tau, appeared in JBC online...
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A study first summarized in our SfN conference news, on post-translational modifications of the protein tau, appeared in JBC online...
Spinocerebellar ataxias (SCAs) are a group of inherited neurodegenerative diseases that...
Researchers studying brain development have identified a key transcription factor that drives...
They are no match made in heaven, but in neurons, the two proteins responsible for amyloid plaques and neurofibrillary tangles might...
Dendritic spines are rapidly becoming the darling of neuroscientists...
Last week, the journal Science formally retracted two stem cell papers published by Woo Suk Hwang and colleagues...
Raging autoimmune T cells were fingered as the culprits in the toxicity of the failed first-generation Alzheimer disease (AD) vaccine. Even so...
The <a href="http://www.aging-institute.org" target="_new">Institute for the Study of Aging</a> (ISOA), Ltd. has changed its name to...
Reduced activity of p21-activated kinase (PAK) may cause the synaptic defects that leave Alzheimer patients with poor memory and cognitive skills...
As the roster of substrates for the γ-secretase protease continues to swell, the presenilin (PS) proteins seem to be...
The drug memantine is a safe and effective therapy that helps patients suffering from moderate to severe Alzheimer disease for up to a year. However...
The word "plasticity" means different things to different people. One of its common uses refers to...
A paradox has plagued Alzheimer disease (AD) researchers for quite some time: People with AD have...
The genetic expansion of internal polyglutamine sequences in several proteins renders them...
Ever since encephalitis halted development of Elan’s active vaccine for Alzheimer disease...