Linking Leptin to AD
Though there is already plenty of evidence linking lipid metabolism and obesity to Alzheimer disease (AD) and other neurodegenerative diseases, the case just got stronger...
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Though there is already plenty of evidence linking lipid metabolism and obesity to Alzheimer disease (AD) and other neurodegenerative diseases, the case just got stronger...
The link between protein aggregation and neurodegenerative diseases is certainly a hot topic these days, awash with questions over whether reducing aggregation is a good idea...
Two articles from the past week describe very different approaches to therapy for Parkinson disease...
This report summarizes discussions and recommendations made at the fourth annual workshop on Enabling Technologies for Alzheimer's disease (AD), held in August 2004 in Bar Harbor, Maine.
Major points of discussion and ideas for future directions from the Enabling Technologies for Alzheimer's Disease 2004 Workshop in Bar Harbor, Maine.
This is a list of final recommendations for future actions from the Enabling Technologies for Alzheimer's Disease Workshop in Bar Harbor, Maine.
Enabling Technologies 2004 Workshop Summary Major Points of Discussion and Ideas for Future Directions List of Final Recommendations from Bar Harbor Enabling Technologies for Alzheimer Disease Research: 2004 Bar Harbor Workshop
Among its many reputed transgressions, amyloid-β is suspected of interfering with synaptic function from the earliest stages of Alzheimer disease...
Finding an easily measurable antecedent marker for Alzheimer disease would be a major development. Might glycogen synthase kinase fit the bill?...
Researchers studying the ubiquitination pathway may be interested in a new technique that can measure ubiquitination—and deubiquitination—in real time...
Various antibiotics have been shown to protect against neurodegenerative diseases, not necessarily through antimicrobial action. Can one of them, rifampicin, prevent the formation of α-synuclein aggregates?...
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Surveying the protein profile of a tissue or body fluid by traditional methods has not proven a very efficient way to detect changes in protein levels in neurodegenerative diseases...
Since the discovery that one peptide, amyloid-β, is the major constituent of amyloid plaques, there has been a tremendous focus on the N-terminal end of amyloid-β precursor protein...
Fragile X mental retardation, the most common form of inherited mental impairment, is caused by mutations in the fmr-1 gene, coding for fragile X mental retardation protein...