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Pushing Longevity to the Max

In today's Science, Cynthia Kenyon and colleagues at the University of California, San Francisco, report that they have generated transgenic nematodes, <em>Caenorhabditis elegans</em>, that live six times longer than normal, the equivalent of about a 500-year lifespan in humans...

Lipid Membranes—Order from Chaos

In yesterday's Nature, Tobias Baumgart and colleagues shine some light on the fluid dynamics of biomembranes using two-photon microscopy to visualize lipids that separate into coexisting liquid phases, or domains, in giant unilamellar vesicles...

Soluble Aβ: Getting a Grip on Its Fate

In Alzheimer’s patients, a portion of soluble amyloid-β peptides (sAβ) never makes it out of the brain as in normal subjects, ending up instead in amyloid fibrils or plaques. A trio of recent papers explores factors that determine the fate of these peptides...

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