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Evidence is accumulating that certain activities are correlated with a reduced risk of Alzheimer's disease, though whether this relationship is one of cause and effect is still open to debate. Recent articles have demonstrated this link...
In theory, genetic manipulation is the only permanent method of altering the biochemistry of somatic cells. In practice, the concept faces many hurdles, not least being a safe and accurate method of delivering the right gene to the right place...
Just as immunotherapy for Alzheimer's disease has encountered its first problems in the clinic, new approaches are emerging in the research pipeline...
The Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT), a clinical research study that will test a possible link between the use of certain anti-inflammatory pain relievers and...
Magnetic resonance imaging (MRI) of the brain shows great promise as a diagnostic tool. Neurodegenerative and psychiatric disorders can lead to changes in the brain that this imaging technique can pick up...
At the Society for Neuroscience meeting last November in San Diego, the Alzheimer Research Forum reported on insulin-degrading enzyme as a potential risk factor for late-onset Alzheimer's disease...
Parthenogenesis, the development of an unfertilized egg into an embryo, has been demonstrated in mice and cows. Although such embryos have never been cultured to full-term, they could provide a valuable source...
Drugs called cholinesterase inhibitors have shown modest benefits for patients with mild to moderate Alzheimer's. In the February Annals of Neurology, researchers led by Steven DeKosky challenge the prevailing theory of how these drugs work...
The growth and development of transplantable neurons from embryonic stem (ES) cells could potentially have immense value for those suffering from neurodegenerative diseases...
Despite much research, it has been difficult to pin down precisely how inflammation contributes to Alzheimer's disease. This endeavor is now drawing fresh support from single nucleotide polymorphism (SNP) analysis...
Researchers have synthesized a series of small chemicals that could become the starting point for a drug development effort aimed at inhibiting inflammatory changes in glial cells without affecting inflammation elsewhere in the body...
More women than men have Alzheimer's disease (AD), suggesting that loss of estrogen may increase the risk for AD in postmenopausal women. Recent studies to demonstrate that estrogen protects Alzheimer's patients have had mixed results...
Amyloid (Aβ), deposited as the major component in the plaques found in Alzheimer's brains, is a product of sequential cleavage of the amyloid precursor protein...
In the upcoming print issue of the Journal of Medicinal Chemistry, Italian researchers led by Allesandro Dalpiaz are reporting initial success in using Vitamin C to ferry drugs through the blood-brain barrier...
Elan Corporation announced last Thursday that it would temporarily suspend further drug administration in the clinical phase 2A trial of its therapeutic vaccine AN-1792...
