Randall Bateman Wins Potamkin Prize
Award recognizes his contributions to basic and clinical research.
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In Year Three, GAP Trial Network Is Starting to Hum
With three trials and initiatives to boost recruitment, GAP-Net is gaining some traction in the field.
FDA Panel Rejects Neuronix Brain Stimulation Device
Experts said Phase 3 data did not prove the device could slow AD.
NIH Summit Sets Agenda for AD-Related Dementias
Among 20 focus areas, 47 research recommendations cover the gamut from basic science to health disparities.
TREM2: Diehard Microglial Supporter, Consequences Be DAMed
At Keystone, the work of several groups painted TREM2 as a dedicated supporter of microglial function across neurodegenerative disease models, including those for ALS.
Turning Peripheral Stem Cells into Amyloid-Gobbling Brain Phagocytes
Screen identifies antibody that induces mouse bone marrow cells to differentiate and travel to the brain, where they clear plaques.
Results from IDEAS Study Published
A majority of amyloid PET scans led physicians to change how they managed a patient’s disease. The effect on later outcomes is yet to be come.
Resetting Brain Rhythms Gives Working Memory a Brief Boost
Transcranial, alternating electrical current restored neuronal synchrony in older people, rejuvenating working memory. For an hour or two.
Second Look at BAN2401 Data Still Positive, Despite Snafu
Subgroup analysis addresses APOE4 randomization imbalance, claims treatment with this anti-Aβ protofibril antibody slowed cognitive decline.
Scientists Hunting Rare Alzheimer’s Mutations Eye Phospholipase D3
Hunting for rare mutations that cause dementia, researchers have spotted, but not yet snagged, some tantalizing candidates.
The Power of Three: Genetic Trios Yield ALS Gene Candidates
The May 26 Nature Neuroscience online debuts 25 new candidate genes for amyotrophic lateral sclerosis...
At AD/PD Conference, New Alzheimer’s Genes Reinforce Known Pathways
After years of grunt work on next-gen sequencing and expression analysis, geneticists are finally reaping results. The new genes underscore the role of known pathways and cell types in disease.
APP Upp: Mutation Nixes Six Amino Acids from Aβ, Spurs Aggregation
Presented at AD/PD, the discovery by scientists in Uppsala is the first APP deletion found to cause Alzheimer’s disease. The same group found the Swedish and Arctic APP mutations.
Older Children with Spinal Muscular Atrophy Improve on Nusinersen
Long-term treatment with the anti-sense oligonucleotide led to motor benefits in an extension trial of children 2 to 15 years old.
New Money to Spur Tech Search for AD Biomarkers
Diagnostics Accelerator to fund projects that develop dementia biomarkers from patient data.
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