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JNK Clogs Axonal Transport

In a paper just out online in Nature Neuroscience, Scott T. Brady et al. report that the polyQ expanded androgen receptor (the cause of spinal bulbar muscular atrophy) inhibits fast axonal transport by activating the c-jun N-terminal kinase (JNK), which phosphorylates the kinesin heavy chain subunit...

Eisbee Conference 2006

Tall Science at Small Retreat: Dispatch from Germany’s Eibsee Oligomers Abound, But Where’s the Seed? γ-Secretase: Ins and Outs of a Voracious Membrane Protein Grinder First Look at the Secretase, New Kid on the Block Assembly, Traffic Escorts, Fats All C

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