Long-Lived and Sharp Through "Good" Cholesterol?
Want to survive to a ripe old age and still manage that cryptic crossword puzzle? Boosting your...
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Want to survive to a ripe old age and still manage that cryptic crossword puzzle? Boosting your...
High-throughput screening for small molecules that prevent neurodegeneration is a relatively new undertaking but growing rapidly...
Pathogenic proteins bearing expanded polyglutamine (polyQ) repeats are causative factors in...
Cold Spring Harbor: How Can We Improve Clinical Trial Design? Cold Spring Harbor: A Grab Bag from the Drug Discovery Folks Neurodegenerative Diseases: Biology and Therapeutics
Drug discovery for neurodegenerative diseases continues on all fronts, from...
Much as tau appears loath to give up its secrets, two recent papers reveal new...
As the pipeline fills with potential therapies for Alzheimer (AD) and other neurodegenerative diseases, the research community is paying increased attention to...
If exercising the body can protect against diabetes and heart disease, then perhaps exercising the brain may protect against cognitive decline...
Testosterone levels decline as men age, and the urge to treat this natural process with hormone replacement has sparked controversy...
A new study in yesterday’s New England Journal of Medicine shows that PET imaging using the amyloid-binding agent FDDNP can...
The prospects of using cerebrospinal fluid biomarkers to diagnose Alzheimer disease may have just gotten a bit brighter...
Feeding an extract of Ginkgo biloba leaves reduced the levels of soluble Aβ oligomers and the pathological effects of amyloid-β (Aβ) expression in...
Researchers thought they had dealt their newborn mice a death blow by deleting the Numb and Numb-like genes in the neural progenitor cells of the subventricular zone...
One of the earliest signs of amyloid-β (Aβ) toxicity is synaptic loss, and recent work from a number of labs has shown that...
The human ApoE4 isoform is the biggest single risk factor for sporadic Alzheimer disease (AD)...