Retinal Gene Therapy Trial Posts Positive Result
Vision improved in some retinitis pigmentosa patients in a Phase 1 trial.
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PET Tracer Detects Synapse Loss Across Alzheimer’s Brain
New research presented at the HAI conference also finds links between UCB-J uptake and plaques, tangles, and cognitive decline.
Can PET Match Up Areas of Protein Deposit With Alzheimer’s Symptoms?
Amyloid and tau PET are helping scientists pinpoint the underlying cause of specific AD symptoms. Perhaps imaging of certain brain regions will help predict an individual’s progression.
How Much Amyloid Will Kick Off Tangles, and Decline?
At HAI 2020, scientists more precisely quantified the relationship between plaques, tangles, and cognitive decline.
Is Too Much Vitamin B12 a Health Hazard?
When observed over an eight-year period, people with the highest plasma concentrations were more likely to die than people with lower levels.
Tau2020: Meeting for Tauopathies Debuts Genetic Variants
By engaging scientists studying every tau-based disorder, a new conference aimed to foster collaborations and research directions.
Human Amyloid Imaging 2020
PET Tracer Detects Synapse Loss Across Alzheimer’s Brain Multimodal Imaging of Neurodegenerative Diseases Links Pathology and Cellular Dysfunction Tau PET: The Field Expands Rapidly Can PET Match Up Areas of Protein Deposit With Alzheimer’s Symptoms? How ...
Tau2020 Global Conference
Tau2020: Meeting for Tauopathies Debuts Genetic Variants Behold the First Human α-Synuclein CryoEM Fibril Structure New at Tau2020: PET Detects First Traces of Tangles in Rhinal Cortex Primary Tauopathies Get New PET Ligands Tau Receptor Identified on ...
Paper Alert: Mouse TREM2 Antibody Boosts Microglial Plaque Clean-Up
The monoclonal antibody activated TREM2 signaling on mouse microglia. It supported their survival and stimulated their clearance of amyloid plaques.
New at Tau2020: PET Detects First Traces of Tangles in Rhinal Cortex
Not sure where that is? You are not alone. It is a tiny spot deep behind the nose, newly defined by the PET signal of early neurofibrillary tangle deposition. It also prompted a tau-staging scheme.
Dementia Research Institute to Double U.K. Coronavirus Testing
United Kingdom’s DRI pivots to fight COVID-19. The facility could test 10,000 samples per day.
Primary Care Physicians Unprepared to Handle Future Alzheimer’s Case Loads
A survey conducted by the Alzheimer’s Association finds that three-quarters of these physicians had little to no residency training in dementia care.
A ‘Perfect Storm’ for Families Grappling with Dementia
From caregivers going it alone to understaffed nursing homes on lockdown, people with neurodegenerative disease and their caregivers are feeling enormous strain from the novel coronavirus. They are adapting to the new normal with technology.
A Phospho-Tau Plasma Assay for Alzheimer’s?
Two papers report that phosphorylated tau in the blood distinguishes people with AD from healthy controls and from people with frontotemporal and vascular dementias.
Low-Dose Aspirin Does Not Prevent AD, or Slow Cognitive Decline
A trial of nearly 20,000 participants found no benefit over five years.
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