Can Induced Neurons Identify Early Signs of Neurodegeneration?
In patient-derived neurons, tau mutations scupper lysosomes and SORLA shunts APP through different types of endosomes.
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In patient-derived neurons, tau mutations scupper lysosomes and SORLA shunts APP through different types of endosomes.
A plasma assay for Alzheimer’s could radically speed up screening for clinical trials; alas, competing assays don’t measure the same thing.
Changes in the composition of the cerebrospinal fluid and synapses may reveal novel insights into AD pathology.