Data on ASOs, presented recently at the annual meeting of the American Academy of Neurology, depict RNA-based therapies as broadly on the rise in neurodegenerative diseases.
At Quebec conference, researchers considered multiple aspects of herpesvirus biology that may come in to play in AD.
In patient-derived neurons, tau mutations scupper lysosomes and SORLA shunts APP through different types of endosomes.
Can genetics please parse the confusing spectrum of frontotemporal dementias? Whole genome sequences make a start.
CryoEM helps explain how the inhibitory receptors open and close their ion channels.
In Barcelona, data ran the gamut from a few hopeful little hints on new treatments to mixed signals on familiar players, and failed drugs thrown on the scrap heap.