NEALS: Collaboration for a Cure to ALS
In the field of amyotrophic lateral sclerosis (ALS), the Northeast ALS Consortium (NEALS) is the hands-down largest and hardest-working township in North America...
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GAP-Net Site Optimization Conference 2019
In Year Three, GAP Trial Network Is Starting to Hum Getting to Go: GAP-Net Sets Sight on Faster Start Three years after the Global Alzheimer’s Platform (GAP) Foundation launched GAP-Net, a standing network of clinical trial sites optimized for Alzheimer’s ...
Getting to Go: GAP-Net Sets Sight on Faster Start
From central IRBs, certified raters, to local transport: Changes large and small are needed to ramp up drug testing in Alzheimer’s.
Randall Bateman Wins Potamkin Prize
Award recognizes his contributions to basic and clinical research.
In Year Three, GAP Trial Network Is Starting to Hum
With three trials and initiatives to boost recruitment, GAP-Net is gaining some traction in the field.
FDA Panel Rejects Neuronix Brain Stimulation Device
Experts said Phase 3 data did not prove the device could slow AD.
NIH Summit Sets Agenda for AD-Related Dementias
Among 20 focus areas, 47 research recommendations cover the gamut from basic science to health disparities.
TREM2: Diehard Microglial Supporter, Consequences Be DAMed
At Keystone, the work of several groups painted TREM2 as a dedicated supporter of microglial function across neurodegenerative disease models, including those for ALS.
Turning Peripheral Stem Cells into Amyloid-Gobbling Brain Phagocytes
Screen identifies antibody that induces mouse bone marrow cells to differentiate and travel to the brain, where they clear plaques.
Results from IDEAS Study Published
A majority of amyloid PET scans led physicians to change how they managed a patient’s disease. The effect on later outcomes is yet to be come.
Resetting Brain Rhythms Gives Working Memory a Brief Boost
Transcranial, alternating electrical current restored neuronal synchrony in older people, rejuvenating working memory. For an hour or two.
Second Look at BAN2401 Data Still Positive, Despite Snafu
Subgroup analysis addresses APOE4 randomization imbalance, claims treatment with this anti-Aβ protofibril antibody slowed cognitive decline.
Scientists Hunting Rare Alzheimer’s Mutations Eye Phospholipase D3
Hunting for rare mutations that cause dementia, researchers have spotted, but not yet snagged, some tantalizing candidates.
The Power of Three: Genetic Trios Yield ALS Gene Candidates
The May 26 Nature Neuroscience online debuts 25 new candidate genes for amyotrophic lateral sclerosis...
At AD/PD Conference, New Alzheimer’s Genes Reinforce Known Pathways
After years of grunt work on next-gen sequencing and expression analysis, geneticists are finally reaping results. The new genes underscore the role of known pathways and cell types in disease.
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