SfN: Early Steps toward Parkinson Disease Blood Test
Biomarkers are the buzz of the field these days, and the hum was heard inside the beltway at the 35th Annual Conference of the Society for Neuroscience...
ALL NEWS
466 RESULTS
Sort By:
- Most Recent
- Most Commented
Making a Vaccine Work: Profiles, Protein Synthesis, and Synapses
After the Elan-Wyeth phase 2a trial on the AN1792 Aβ vaccine had to be halted because some patients developed meningeal encephalitis, scientists have...
Looking outside the Brain for Early Signs of AD
The use of gene expression profiling to characterize Alzheimer disease pathology has, unsurprisingly, focused on...
Sorrento: They’ve Just Got to Have It—Where’s That Biomarker? Part 1
This is part 1 of a biomarker update from Sorrento.
Sorrento: They’ve Just Got to Have It—Where’s That Biomarker? Part 2
This is part 2 of the biomarker update from Sorrento.
"Bio-Barcode" Amplifies Aβ Oligomer Signal, Proffers Candidate Diagnostic Test
By amplifying small quantities of Aβ oligomer in cerebrospinal fluid, a methodology referred to as the "bio-barcode" could serve as a diagnostic or monitoring test for AD...
GSK-3—A Peripheral Marker for AD?
Finding an easily measurable antecedent marker for Alzheimer disease would be a major development. Might glycogen synthase kinase fit the bill?...
CSF Proteomics Test for ALS?
Surveying the protein profile of a tissue or body fluid by traditional methods has not proven a very efficient way to detect changes in protein levels in neurodegenerative diseases...
New Marker for AD on the Horizon?
The chemokine receptor CCR1 might be an early and specific marker of Alzheimer's disease, researchers suggest in the November issue of Annals of Neurology, now available online...
Biomarker Bonus: Phospho-Tau/Aβ Ratio Increase Sensitivity
The ratio of phosphorylated tau (p-tau) to β-amyloid (Aβ) in the cerebrospinal fluid improves the ability to distinguish clinically defined Alzheimer's patients from normal subjects, according to a study...
Oxidative Damage to the Olfactory Epithelium—Smells Like AD
Could biopsy of olfactory epithelium yield early warnings of Alzheimer's disease (AD)? This possibility was raised by George Perry and colleagues who report that oxidative damage to olfactory neurons could be a harbinger of impending AD...
U.S. Study Questions the Value of CJD Test
Soon after the World Health Organization bestowed its approval on the protein 14-3-3 as an important diagnostic marker for sporadic Creutzfeldt-Jakob disease (sCJD), reports began to come in that its sensitivity and specificity might not be all that was advertised...
Spinal Taps for Tau Tests
Assays of Aβ or tau protein in cerebrospinal fluid can identify Alzheimer's disease in patients with mild cognitive impairment, say the authors of a study in today’s Archives of Neurology...
Orlando: Eyeballing the Eye in the Hunt for That Elusive Prize, an AD Biomarker
Today at the annual meeting of the Society for Neuroscience, <strong>Lee Goldstein</strong> of Massachusetts General Hospital presented evidence suggesting that the Aβ peptide occurs in the eyes of people with Alzheimer’s disease...
More on Biomarkers That Signal Longevity
Humans who live longer display the same biomarkers found in laboratory animals who have restricted caloric intake. However, because these human subjects weren't actively restricting their caloric intake, there may be other ways to increase life span in humans...