Hot Plasma—Blood Aβ a Risk Marker for AD?
Among the plethora of factors that might serve as useful biomarkers for AD, perhaps none draws as much scrutiny as plasma amyloid-β...
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BACE1 Gets Attention as Potential Alzheimer’s Biomarker
Recent work indicates that CSF BACE activity is significantly increased in people with AD...
eFAD News: Biomarkers May Help Pinpoint Disease Onset
People affected by early-onset familial forms (eFAD) often wonder how discoveries apply to them...
Plasma Aβ Testing Beset by Questions of Assays, Biology, Timing
Researchers led by Oskar Hansson at Lund University, Sweden, have developed a highly sensitive assay for plasma Aβ...
Metabolomics Reveals Changes in CSF in Model of HIV Dementia
A scan of cerebrospinal fluid from SIV-infected monkeys turned up potential markers of central nervous system disease...
A New Test for Alzheimer Disease?
A company recently announced that it will start marketing a blood test for Alzheimer disease within the year...
Alzheimer Activism: How To Modernize Clinical Trials?
On March 13, Alzheimer disease activist groups met with representatives from the FDA, clinicians, and industry leaders to discuss ways to improve clinical trials for candidate AD drugs...
A Blood Test for AD?
Plasma cholesterol measurements have done wonders for cardiovascular disease management...
AD Diagnosis: Time for Biomarkers to Weigh In?
Is it time for a new diagnostic paradigm for Alzheimer disease?...
The Value of Biomarkers—Diagnosis and Genetic Screens
Much hope rides on the diagnostic and prognostic ability of biomarkers, exemplified by...
Biomarker Roundup: Collecting Clues from MRIs to RNAs
A batch of stories this week spans current approaches to biomarkers being developed for early detection of Alzheimer disease...
Cold Spring Harbor: How Can We Improve Clinical Trial Design?
As the pipeline fills with potential therapies for Alzheimer (AD) and other neurodegenerative diseases, the research community is paying increased attention to...
CSF Biomarkers—Maybe You Can See the Forest for the Trees
The prospects of using cerebrospinal fluid biomarkers to diagnose Alzheimer disease may have just gotten a bit brighter...
Brains in Transition: Signposts Point the Way from MCI to Alzheimer Disease
This month’s Archives of Neurology provides a gold mine of studies on the neuropathological correlates of...
ALS—Study Strengthens VEGF Connection, Potential Biomarkers Proffered
A diagnosis, let alone a cure, for amyotrophic lateral sclerosis has proven hard to pin down, but...