Risky Business—New Index Predicts Dementia in Older Adults
Unfortunately, there is no quick test for predicting Alzheimer disease (AD)—at least not yet...
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News Brief: Scientists Net Prizes for Progress Toward ALS Biomarker
The nonprofit Prize4Life is awarding two scientific teams with $50,000 each at the American Academy of Neurology annual meeting in Seattle, Washington, this week...
Studies Reveal New Hope, Old Problems With AD Biomarkers
Brain imaging and cognitive tests may be the gold standards for tracking AD progression, but clinical trials using these procedures are expensive, risky, and time-consuming...
ADNI: GWA Nearly Complete, Biomarker Analysis Update
The Alzheimer’s Disease Neuroimaging Initiative announced this week that its genomewide analysis is 95 percent complete...
Keystone: Pulse-Chasing AD Biomarkers, Snaring γ-Secretase Targets
Two things you can find on any Alzheimerologist’s wish list are better drug targets and better diagnostics...
Research Brief: New Methods for Aβ Detection, Production
So many different Aβs to measure, so little time—and funds...
DIAN Part 2: The Science, Inner Workings of the Network
Scientifically, the Dominantly Inherited Alzheimer Network (DIAN) will test three hypotheses...
Worldwide ADNIs: Other Nations Follow Suit
Around the time the North American ADNI started, similar efforts sprang up in countries across the globe...
Bumps Along the Way—ADNI’s Snafus
By common consensus of some 20 investigators contacted for this story from within and without ADNI, this behemoth study is working well overall...
More ADNI Results 2: It’s All About Power
One goal of ADNI is to make clinical trials sharper...
Hot Plasma—Blood Aβ a Risk Marker for AD?
Among the plethora of factors that might serve as useful biomarkers for AD, perhaps none draws as much scrutiny as plasma amyloid-β...
BACE1 Gets Attention as Potential Alzheimer’s Biomarker
Recent work indicates that CSF BACE activity is significantly increased in people with AD...
eFAD News: Biomarkers May Help Pinpoint Disease Onset
People affected by early-onset familial forms (eFAD) often wonder how discoveries apply to them...
Plasma Aβ Testing Beset by Questions of Assays, Biology, Timing
Researchers led by Oskar Hansson at Lund University, Sweden, have developed a highly sensitive assay for plasma Aβ...
Metabolomics Reveals Changes in CSF in Model of HIV Dementia
A scan of cerebrospinal fluid from SIV-infected monkeys turned up potential markers of central nervous system disease...