Falling CSF Synuclein a Harbinger of Parkinson’s Disease?
The last decade has seen study after study confirm that falling amyloid-β (Aβ) in the cerebrospinal fluid (CSF) is an indicator of incipient AD...
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The last decade has seen study after study confirm that falling amyloid-β (Aβ) in the cerebrospinal fluid (CSF) is an indicator of incipient AD...
A painless test of muscle conductivity promises to make clinical trials for amyotrophic lateral sclerosis (ALS) smaller, cheaper, and faster...
For anyone in an AD study who is nervous about a spinal tap, the idea of measuring dementia risk with a simple blood test would be a dream come true...
A new strategy for detecting serum antibodies could have important ramifications for Alzheimer’s disease diagnostics...
Researchers report stark differences among cognitively normal people enrolled in the Alzheimer’s Disease Neuroimaging Initiative...
Speakers focused on the Coalition Against Major Diseases’ goal of garnering approval for biomarkers in AD drug development...
In an ideal future, physicians would diagnose people with incipient Alzheimer’s disease long before memory problems appear...
Part 2 of Alzforum’s coverage continues with what scientists from inside and outside DIAN said about the prospect of such pre-symptomatic trials...
The few people who have an ApoE2 allele enjoy reduced risk of late-onset Alzheimer’s disease...
Frontotemporal dementias pose a challenge for diagnosis because numerous overlapping clinical syndromes are associated with the disease...
Small, soluble oligomers of amyloid-β (Aβ) are now widely believed to be the most toxic form of the peptide...
PPMI was launched in July with hopes of identifying a biomarker, or set of markers, that tracks the natural course of Parkinson disease...
One of the great challenges with developing treatments for neurodegenerative disorders stems from the capricious nature of disease progression...
The majority of patients with Parkinson disease eventually develop dementia, but what pathology underlies this decline?...
In clinical research, a first-time finding may rouse intrigue, but it’s generally independent confirmations of the data that give them potential to leave an indelible mark...