New Neuropathologic Guidelines for AD Almost Ready for Primetime
New U.S. guidelines for the neuropathologic assessment of Alzheimer’s disease (AD) and related conditions are getting close to being finalized...
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EU Consortium Applies Nanotechnology to Study AD
Researchers are starting to see opportunities for nanomedicine, the application of nanoscale materials and processes to medical problems, in AD...
Are Soluble APP Fragments Markers for ALS?
Readers could be forgiven for doing a double-take at the title of a recent paper linking APP—best known for its role in Alzheimer’s disease—to ALS...
Paris: Standardization a Hurdle for Spinal Fluid, Imaging Markers
In the fall of 2009, a large quality control (QC) program started comparing measurements of cerebrospinal fluid (CSF) biomarkers from labs across the world...
"Autoantibody-omics" Yields Potential Blood Biomarkers for AD
Though Alzheimer’s is not typically considered an immune disease, serum autoantibodies just may hold promise as a blood-based AD diagnostic...
Soluble APP, Glycosylated Fragments Correlate With AD
Having established the first 42 amino acids in Aβ as a valid biomarker for AD, researchers are now turning their attention to all the other fragments of APP in the CSF...
Can Diet Influence Alzheimer’s Disease Biomarkers?
You are what you eat, the old saying goes. This may be particularly true for the brain...
Overblown Biomarkers: Are Publication, Funding Practices to Blame?
In the biomarker field, potential new indicators of disease risk and prognosis leap onto the scene, yet vanishingly few finish the journey to routine clinical use...
Little by Little—Standardizing, Validating Those Biomarkers
Biomarkers stand poised to transform Alzheimer’s research, but scientists first must iron out pesky technical issues and ensure that markers give reliable, repeatable results...
Revised Diagnostic Criteria for Alzheimer’s Are Published
New diagnostic criteria for Alzheimer’s disease and for its preclinical manifestations formally appeared online today...
Taos: Biomarkers Keep Blooming, But Where’s the Fruit?
Biomarkers could be invaluable diagnostic and prognostic indicators for Alzheimer’s and other neurodegenerative diseases...
Barcelona: Stocking Biomarker Arsenal for Lewy Body Dementia
Dementia with Lewy bodies (DLB) sits at the interface of several disorders...
Detecting Familial AD Ever Earlier: Subtle Memory Signs 15 Years Before
Recent findings have strengthened the scientific underpinning of the Alzheimer’s Prevention Initiative...
Metabolomics: Seeking Biomarkers for ALS, Parkinson’s, Huntington’s
Metabolomics has given researchers studying Alzheimer’s disease plenty to think about...
Metabolomics: The Fourth Great Ome
You could say biological researchers have been binging on omes this past decade...