Paris: Standardization a Hurdle for Spinal Fluid, Imaging Markers
In the fall of 2009, a large quality control (QC) program started comparing measurements of cerebrospinal fluid (CSF) biomarkers from labs across the world...
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"Autoantibody-omics" Yields Potential Blood Biomarkers for AD
Though Alzheimer’s is not typically considered an immune disease, serum autoantibodies just may hold promise as a blood-based AD diagnostic...
Soluble APP, Glycosylated Fragments Correlate With AD
Having established the first 42 amino acids in Aβ as a valid biomarker for AD, researchers are now turning their attention to all the other fragments of APP in the CSF...
Can Diet Influence Alzheimer’s Disease Biomarkers?
You are what you eat, the old saying goes. This may be particularly true for the brain...
Overblown Biomarkers: Are Publication, Funding Practices to Blame?
In the biomarker field, potential new indicators of disease risk and prognosis leap onto the scene, yet vanishingly few finish the journey to routine clinical use...
Little by Little—Standardizing, Validating Those Biomarkers
Biomarkers stand poised to transform Alzheimer’s research, but scientists first must iron out pesky technical issues and ensure that markers give reliable, repeatable results...
Revised Diagnostic Criteria for Alzheimer’s Are Published
New diagnostic criteria for Alzheimer’s disease and for its preclinical manifestations formally appeared online today...
Taos: Biomarkers Keep Blooming, But Where’s the Fruit?
Biomarkers could be invaluable diagnostic and prognostic indicators for Alzheimer’s and other neurodegenerative diseases...
Barcelona: Stocking Biomarker Arsenal for Lewy Body Dementia
Dementia with Lewy bodies (DLB) sits at the interface of several disorders...
Detecting Familial AD Ever Earlier: Subtle Memory Signs 15 Years Before
Recent findings have strengthened the scientific underpinning of the Alzheimer’s Prevention Initiative...
Metabolomics: Seeking Biomarkers for ALS, Parkinson’s, Huntington’s
Metabolomics has given researchers studying Alzheimer’s disease plenty to think about...
Metabolomics: The Fourth Great Ome
You could say biological researchers have been binging on omes this past decade...
Falling CSF Synuclein a Harbinger of Parkinson’s Disease?
The last decade has seen study after study confirm that falling amyloid-β (Aβ) in the cerebrospinal fluid (CSF) is an indicator of incipient AD...
News Brief: Muscle-Monitoring Method Earns $1 Million ALS Prize
A painless test of muscle conductivity promises to make clinical trials for amyotrophic lateral sclerosis (ALS) smaller, cheaper, and faster...
In the Blood: What Can Plasma Aβ Tell Us About Alzheimer’s?
For anyone in an AD study who is nervous about a spinal tap, the idea of measuring dementia risk with a simple blood test would be a dream come true...