Testosterone Therapy for Men with Alzheimer Disease?
For years, postmenopausal women have agonized over the risks and benefits of estrogen replacement therapy. Now comes a hint that elderly men might benefit...
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For years, postmenopausal women have agonized over the risks and benefits of estrogen replacement therapy. Now comes a hint that elderly men might benefit...
Evidence is accumulating that certain activities are correlated with a reduced risk of Alzheimer's disease, though whether this relationship is one of cause and effect is still open to debate. Recent articles have demonstrated this link...
This year’s 35th annual meeting of the Society for Neuroscience had groups of researchers share a common sense of excitement about...
Just where in the pathogenic process tau deals cells their death blow is a topic of much debate and research. Two studies published this week take a closer look. Brandt et al. report on the effects of a pseudohyperphosphorylated tau mutant in hippocampal slice cultures...
Expansion of the polyglutamine (polyQ) tract in the huntingtin protein is necessary to cause Huntington disease, but it is not...
Cerebellar ataxias form a large group of movement and balance disorders that result from degeneration of Purkinje cells...
Papers in tomorrow’s Cell and last week's Neuron reveal that protein phosphorylation plays a key role in spinocerebellar ataxia type 1 (SCA-1), an ultimately fatal neurodegenerative disease marked by progressive loss of muscle control...
The appearance of clots of abnormal proteins inside neurons is characteristic of...
The prospects of using cerebrospinal fluid biomarkers to diagnose Alzheimer disease may have just gotten a bit brighter...
In this week's Journal of the American Medical Association, researchers report a correlation between Alzheimer's disease (AD) and the appearance in the cerebrospinal fluid (CSF) of two proteins thought to play major roles in the progression of the disease—amyloid β42 (Aβ42) and tau...
A paradox has plagued Alzheimer disease (AD) researchers for quite some time: People with AD have...
Biomarkers are the buzz of the field these days, and the hum was heard inside the beltway at the 35th Annual Conference of the Society for Neuroscience...
The use of gene expression profiling to characterize Alzheimer disease pathology has, unsurprisingly, focused on...
Two recent reports add to the growing evidence that trouble in the circulatory system can lead to...
Mutations in mitochondrial DNA (mtDNA) accumulate in aging and Alzheimer disease, but their impact on cell physiology...
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