Keystone Symposia Meeting, Part 5—β-secretase
In part 5 of our report, Minji Kim, Alice Lu, and Rudy Tanzi summarize some new data on β-secretase, including...
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Presenilins Work Overtime to Control Akt, Tau, and Aβ—n-3 Fatty Acids Aid and Abet
The job description of presenilins (PS) in the business of neuron health and disease may be getting more complicated...
Fish Oil Swims Ahead in Dietary Brain Protection Race
Organism-level experimental data now lend some support to the epidemiologic evidence that the fatty acids in fish oil can protect against Alzheimer disease...
First Look at the Secretase, New Kid on the Block
Part 4 of our 11-part Eibsee conference series.
Immunotherapy Interrupted—Inflammation by Interferon
Could interferon-γ (IFN-γ) be to blame for the encephalitis that brought an end to clinical trials of Elan’s amyloid-β (Aβ) vaccine?...
Immunotherapy Protects against Synaptic Effects of Soluble Amyloid-β Oligomers
Originally, vaccination with amyloid-β (Aβ) peptides aimed to fight Alzheimer disease by...
Sorrento: Immunotherapy Update Hot Off Lectern of AD/PD Conference
Yesterday, the 7th International Conference on Alzheimer’s and Parkinson’s disease—AD/PD 2005 for short—drew to a close in beautiful Sorrento, Italy...
No Pressure, But Could Hypertension Medication Prevent AD?
They have been used for decades to lower blood pressure, but evidence now suggests that some specific forms of diuretic drugs may...
Oligomers Abound, But Where’s the Seed?
Part 2 of our 11-part Eibsee conference series.
Assembly, Traffic Escorts, Fats All Control APP Processing
Part 5 of our 11-part Eibsee conference series.
Shedding Assumes α Status
Part 6 of our 11-part Eibsee conference series.
An Intricate Dance: α-Secretase and Its Partners
Part 7 of our 11-part Eibsee conference series.
γ-Secretase: Ins and Outs of a Voracious Membrane Protein Grinder
Part 3 of our 11-part Eibsee conference series.
Mapping Protein Networks in the Roundworm
Genome, transcriptome, proteome, and now we have the interactome, the full complement of protein-protein interactions that can occur in the cell...
Mapping Interactions in the Drosophila Proteome
Researchers have identified over 20,000 different interactions among over 7,000 proteins that are coded in the genome of the fruit fly <em>Drosophila melanogaster</em>, allowing them to create extensive and intricate protein-protein contact maps...
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