Neuronal Plasticity the Arbor Way—Dendritic Remodeling in the Neocortex
The word "plasticity" means different things to different people. One of its common uses refers to...
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Brain Imaging Speaks Volumes about AD and the Aβ Sink
A paradox has plagued Alzheimer disease (AD) researchers for quite some time: People with AD have...
Huntingtin and Transcription: A Story of the Incredible Shrinking CAG Repeats
The genetic expansion of internal polyglutamine sequences in several proteins renders them...
Passive Aggressive—Must Antibody Therapy Start Early to Be Effective?
Ever since encephalitis halted development of Elan’s active vaccine for Alzheimer disease...
Society for Neuroscience Annual Meeting 2005
SfN: R-Flurbiprofen Phase 2 Trial Results SfN: How to Dispose of Plaques? Closing Spigot Won’t Do; Enzymes Nibble SfN: Return of the Other—Tau Is Back, Part 1 SfN: Return of the Other—Tau Is Back, Part 2 SfN: Return of the Other—Tau Is Back, Part 3 SfN: R
Secretion of SOD1 Mutant Proteins Tied to ALS
In amyotrophic lateral sclerosis (ALS), motor neurons in the spinal cord and central nervous system die off for unknown reasons...
SfN: EPO—Not Just for Blood Cells Anymore, but Neurons, Too
Erythropoietin (EPO), produced by the kidney in response to low serum oxygen, is a major stimulant for...
Paper Alert: Synaptic Activity Increases Aβ Release
Today, a study summarized in our SfN Conference News appeared in Neuron...
Delphi Consensus Foresees Sharp Rise in World Dementia
The oracle at Delphi had legendary powers of foresight. But would the prophetess have predicted a staggering...
APP Double Dose Causes Early Onset AD
For the first time, researchers have identified duplications of the amyloid precursor protein (APP) gene locus...
Senior Author Requests Retraction of Cloning Paper
Last May, researchers made a splash when they reported that they had succeeded in making 11 different human clones...
SfN: Channeling Selective Toxicity in Parkinson Disease
One of the puzzles of Parkinson pathology is why death comes to only a subpopulation of neurons in the midbrain...
Testosterone Therapy for Men with Alzheimer Disease?
For years, postmenopausal women have agonized over the risks and benefits of estrogen replacement therapy. Now comes a hint that elderly men might benefit...
Aβ—Dutch Mutation Throws Peptide for a Loop
What makes amyloid-β (Aβ) polymerize?...
SfN: Nature or Nurture—Epigenetics in Neuronal Responses
Take a break from Aβ and tau, and consider something completely different...
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