Surprise! Some γ-Secretase Modulators Work by Targeting APP
mimic Aβ40 in its ability to prevent Aβ42 aggregation.—Esther Landhuis None
379 RESULTS
You searched Esther
Sort By:
mimic Aβ40 in its ability to prevent Aβ42 aggregation.—Esther Landhuis None
ability to kill neurons.”—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2602
fully effective against late-onset AD.”—Esther Landhuis None
the researchers examine older mice with plaque pathology.—Esther Landhuis None
earlier this fall, and should be completed by late 2011, Koenig said.—Esther Landhuis. None
in an e-mail to ARF.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2415
carriers ultimately show slower rates of mental decline, compared to people with E3 or E4 alleles.—Esther
person-centered care of the people with dementia and their family members.”—Esther Landhuis None
Preliminary data from other labs suggest the mechanism operates in SCA7 and HD as well.—Esther Landhuis None
proteins, thus to neurodegenerative disease, not only AD,” Pahnke said.—Esther Landhuis None
whether any of this work relates to cells in their native context,” he told ARF.—Esther Landhuis None
PD, whereas by virtue of its binding SorLA, Vps26 is more linked to APP and AD.—Esther Landhuis None
Sciences (see Science article).—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=3413
intracellular location of the presumed Aβ oligomers influences cognition in this model.—Esther Landhuis None
influence disease risk through multiple mechanisms, can also be problematic.—Esther Landhuis None