Abnormal Mitochondrial Dynamics—Early Event in AD, PD?
mitochondrial distribution abnormalities can lead to synaptic deficits in vivo.—Esther Landhuis None
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Upping Brain ApoE, Drug Treats Alzheimer's Mice
to develop AD therapeutic compounds that promote Aβ clearance without actually entering the brain.—Esther
Will Tau Drug Show Its True Colors in Phase 3 Trials?
in 2002 with Kwang Meng Seng, a physician and venture capitalist.—Esther Landhuis. Q&A With Claude
Reelin, Aβ, α7 Play Yin and Yang Around NMDA Receptors
Future research will show how this reasoning plays out in dynamic, complex in vivo systems.—Esther
Circuit Menders? Neurogenesis, Stem Cells Show Potential
to see which one is going to be superior over the others.”—Esther Landhuis None
BACE Inhibitors Hitch Ride into Endosomes via Membrane Anchor
intraventrically can produce effects comparable to direct injections into the hippocampus.—Esther Landhuis Esther
Blunted Sense of Smell Parallels Pathology in AD, PD
dysfunction in AD mouse models as a tool to track changes in AD-related pathologies," Wesson said.—Esther
Scouting AD’s “Little League” Genes: Can Systems Biology Help?
to go.”—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=1829 Alzheimer's Disease Genetics
Inducible APP Mice—Cognition Restored in Advanced Amyloidosis?
oligomers influences cognition in this model.—Esther Landhuis None
Inside Out—Plaques May Have Intracellular Origin
fibrils (Frost et al., 2009; Ren et al., 2009), Lee said.—Esther Landhuis None
HAI Chicago: PIB in Healthy People
imaging techniques as well as biological and neuropsychological tests.—Esther Landhuis. This is Part 1
Mice, Flies Further Implicate Retromer in AD Pathogenesis
to reduce Aβ production,” Small said.—Esther Landhuis Esther Landhuis is a science writer in Dublin,
Dual Secretase Approach Shows Promise in AD Mice
is expected to be beneficial in conditions associated with increased levels of BACE1.”—Esther Landhuis None
Antioxidants No Help for Alzheimer’s, Biomarker Trial Says
not have plans to test antioxidants in milder AD or at-risk, asymptomatic populations.—Esther Landhuis None
AD Immunotherapy: Toward Prevention, DNA-based Vaccines?
and join the discussion.—Esther Landhuis. Esther Landhuis is a science writer in Dublin, California.