The Essence of Time—Memory Studies Tackle Fourth Dimension
memories are differentially processed during sleep and wakefulness, see Robertson, 2009).—Esther Landhuis
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Nuclear Pore Complexes Built to Last, But Not Forever
brings the nuclear pores, the gateway to the nucleus, into the mix.”—Esther Landhuis None
CAA Relief? Specialized Macrophages Help Flush Out Vascular Amyloid
of CAA.”—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2017 Cerebral Amyloid Angiopathy Immune
PD Studies Highlight Deep Brain Stimulation, New Role for α-Synuclein
in accumulation of inactive MEF2D in the cytoplasm, leaving the neurons more susceptible to death.—Esther Landhuis
Paper Alert—Transcription Factors Regulate Aβ Clearance
of further scrutiny.—Esther Landhuis, Tom Fagan None http://www.alzforum.org/new/detail.asp?id=2001
Clinical Trials—Could Participant Amenities Boost Enrollment?
participants.”—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=1994 Alzheimer's Disease Triplet
DC: Developing But Debatable—Deacetylase Inhibitors for CNS Disease?
and probably a lot safer,” she told ARF.—Esther Landhuis. This is Part 2 of a two-part series. See also Part 1.
Overworked HDACs Leave Transcriptional Posts to Push DNA Repair
For a glimpse at several promising HDAC-targeted drug candidates, read Part 2 of this series.—Esther Landhuis
DC: Amyloid-Laden Brains—What Do They Mean for Healthy Seniors?
he said.—Esther Landhuis. None http://www.alzforum.org/new/detail.asp?id=1982 Alzheimer's
DC: Primate, Mouse Studies Sustain Aβ Immunotherapy Hopes
don't have amyloid deposition in their blood vessels.”—Esther Landhuis. None
DC: Aβ Clearance—Roles for MBP, Transcription Factors?
receptor-related protein 1 (LRP1), a key Aβ clearance receptor (see ARF related news story).—Esther Landhuis. None
Imaging Studies Support Cognitive Reserve Theory
holds up in older people (age 65 and up) lacking overt memory problems.—Esther Landhuis None
SIRT1 Activator Prevents Metabolic Disorders in Mice
ARF.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=1966 Alzheimer's Disease Sirtuins
Sirtuin Inhibitor Boosts Cognition, Reduces Phospho-tau
are safe.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=1962 Alzheimer's Disease Sirtuins Tau
Brain Drain—E4 Less Stable Than Other ApoE Isoforms
in an e-mail to ARF (see full comment below).—Esther Landhuis None