Surprise! Some γ-Secretase Modulators Work by Targeting APP
Aβ36 and Aβ37 might mimic Aβ40 in its ability to prevent Aβ42 aggregation.—Esther Landhuis None
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San Diego: Flexible N-Termini Key to Aβ42 Oligomer Toxicity?
studies.—Esther Landhuis. None http://www.alzforum.org/new/detail.asp?id=2630 Alzheimer's Disease Aβ
Research Brief: Auguste D.'s Mutation Identified?
to analyze, noting that such families have been exceedingly hard to find in Germany.—Esther Landhuis None
In Cells, Late- and Early Onset Alzheimer’s Look Different
might not be fully effective against late-onset AD.”—Esther Landhuis None
Aβ and Phospho-tau: Strange Bedfellows Get Intimate at Synapses
of phospho-tau accumulation at sites of Aβ. We want to understand the biology there.”—Esther Landhuis None
Toulouse: Experimental Drug Sensitizes Receptor, Boosts Cognition
for the study. Enrollment began earlier this fall, and should be completed by late 2011, Koenig said.—Esther
Caffeine Rush? Reversing Cognitive Woes, Aβ Load in AD Mice
I'm right on schedule,” he quipped during a recent phone conversation with this reporter.—Esther
Weight, Weight, Don’t Tell Me—Leptin Lowers AD Risk?
of neurodegeneration.”—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2316 Alzheimer's Disease Clinical
Research Brief: More NMDA Receptor Gene Variants in CNS Disease
such as mental retardation, epilepsy, and possibly AD/neurodegeneration.”—Esther Landhuis None
Hearing Loss Linked to Incident Dementia
of dementia more than 10 percent by 2050 (Brookmeyer et al., 2007).—Esther Landhuis None
Las Vegas: Can Collaboration Speed Drug Discovery for FTD?
with the Clinical Trials on Alzheimer’s Disease Conference, 3-5 November 2011 in San Diego.—Esther Landhuis.
"Autoantibody-omics" Yields Potential Blood Biomarkers for AD
are detecting the presence of disease,” Robert Nagele told ARF.—Esther Landhuis None
PET in PD: Grafts Expose Symptoms, Cancer Agent Treats Mice
work and trying to design analogs, Barnham said.—Esther Landhuis None
Aβ42 Oligomers Block Cholesterol Synthesis, Protein Prenylation
of that could be detrimental.”—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=3150
Cortical Changes Precede Hippocampal in ApoE Carriers
cingulate/precuneus cortical thinning than with hippocampal volume loss (Becker et al., 2011).—Esther Landhuis None