Chicago: NFATs, Calcineurin—Mediators of AD, PD Pathogenesis?
a dementia spectrum disorder that combines elements of AD and PD.—Esther Landhuis. None
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PD Studies Suggest Motor Cortex as Treatment Target
mice.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2077 Parkinson's Disease Research
PD Studies Highlight Deep Brain Stimulation, New Role for α-Synuclein
in accumulation of inactive MEF2D in the cytoplasm, leaving the neurons more susceptible to death.—Esther Landhuis
AD Research Participation: Informed Consent Complicates Trials, Part 1
of this story.—Esther Landhuis See also Part 2 of this story. None http://www.alzforum.org/new/detail.asp?id=1867
Insulin Resistance Correlates With Plaque, But Not Tangle, Pathology
the Japanese study.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2545 Alzheimer's
Evidence Piles Up for Presenilins’ Role in Autophagy
that cause familial AD.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2707 Alzheimer's
Seeds of Destruction—Prion-like Transmission of Sporadic AD?
in body fluids, primarily cerebrospinal fluid.—Esther Landhuis None
Divide and Conquer: Structure-Function Victory With Presenilin 1
(see full comment below).—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2431
Feeding Frenzy—Therapeutics Tap Tryptophan, Cathepsins, HDACs, Zinc
group," he wrote in an e-mail to ARF (see full comment below).—Esther Landhuis None
PIB-PET Biomarker Study Confirms Bapineuzumab Lowers Amyloid
of amyloid in aging and dementia, and allow us to test mechanistic hypotheses,” he wrote.—Esther Landhuis
Modeling Sporadic PD in a Dish?
for high-throughput screening for genes or small molecules that eliminate or modify the pathology.—Esther Landhuis
BOLD New Look—Aβ Linked to Default Network Dysfunction
impairment.”—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2209 Alzheimer's Disease Clinical
Chicago: AD and Epilepsy—Joined at the Synapse?
2.—Esther Landhuis. This is Part 1 of a two-part series. See also Part 2. None
Case Dismissed—NIH Rescues JAX From APPswe Patent Suit
be dismissed.”—Esther Landhuis. None http://www.alzforum.org/new/detail.asp?id=2876 Alzheimer's Disease Research
Paper Alert: Intranasal Insulin Data Fuels Push for Phase 2B Trial
cognitive and functional tests, as well as CSF biomarker and imaging endpoints, she told ARF.—Esther