Paper Alert: Intranasal Insulin Data Fuels Push for Phase 2B Trial
cognitive and functional tests, as well as CSF biomarker and imaging endpoints, she told ARF.—Esther
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Paper Alert: PIB-PET, Brain Biopsies Match Well for Detecting Aβ
with AD-like features in this study had severe dementia.—Esther Landhuis None
Merck Launches Largest Trial of BACE Inhibitor in AD
news story). Several other companies, including Eisai, are developing BACE1 inhibitors.—Esther
Vassar, Wolfe, Zlokovic Win 2009 Potamkin Prize
awardees!—Esther Landhuis. None http://www.alzforum.org/new/detail.asp?id=2111 Alzheimer's Disease
Research Brief: New Hues for Calcium Imagers
the authors write.—Esther Landhuis. Click on this image to launch the video. Rat hippocampal neuron expresses
Paper Alert: Microtubule Stabilizer Improves Tauopathy in Mice
infusions.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=3099 Research Models Tau
Research Brief: If the Cap Fits...? Portable Scanners for Rodent PET
functional responses to anti-amyloid medications.—Esther Landhuis None
Research Brief: Auguste D. Did Not Have Volga German Mutation
examples here, see photos in Alois Alzheimer biographical story).”—Esther Landhuis None
New Pathology Criteria Published: Alzheimer’s Without Dementia?
the original charge,” Montine said, noting they will not specify a protocol for clinicians.—Esther Landhuis
2009 MetLife Awards Honor Friendly Rivals Iwatsubo, Wolfe
On behalf of the community, the ARF team congratulates this year’s MetLife winners!—Esther Landhuis. None
Research Brief: Did γ-Secretase Mutation Get Under Karl Marx’s Skin?
of a single PSEN1 allele may not be sufficient to cause familial AD,” the authors write.—Esther Landhuis None
Research Brief: Specific Care Plan Does Little for AD Patients
with this care plan and with evidence-based guidelines,” he wrote.—Esther Landhuis None
Patient-Derived Aβ Needs Prion Protein to Harm Synapses
antibodies, Rowan noted.—Esther Landhuis None http://www.alzforum.org/new/detail.asp?id=2797 Alzheimer's
Take It to the Brain Bank—Human Array Tomography Could Pay Dividends
as researchers in the U.K. and Spain, on rodent and human AT studies.—Esther Landhuis None
Research Brief: Structural Rationale for New Tauopathy Drugs
specificity for the tau splicing regulatory element.—Esther Landhuis None