All Comments by Xiongwei Zhu

  1. Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation.
  2. Tau promotes neurodegeneration via DRP1 mislocalization in vivo.
  3. Mitochondrial dynamics and bioenergetic dysfunction is associated with synaptic alterations in mutant SOD1 motor neurons.
  4. Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage.
  5. Caspase activation precedes and leads to tangles.
  6. Cancer linked to Alzheimer disease but not vascular dementia.
  7. Expression of beta-amyloid induced age-dependent presynaptic and axonal changes in Drosophila.
  8. Low uric acid levels in serum of patients with ALS: further evidence for oxidative stress?
  9. Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease.
  10. NO Kidding? Mitochondria Fission Protein Linked to Neurodegeneration
  11. AD Clinical Pipeline: Immunotherapy Woes, Dimebon Boons
  12. Research Brief—Flurizan Fails Final Hurdle, Company Discontinues Drug
  13. Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.
  14. NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease.
  15. Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease.