All Comments by Carl Cotman

  1. Plaque biogenesis in brain aging and Alzheimer's disease. I. Progressive changes in phosphorylation states of paired helical filaments and neurofilaments.
  2. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.
  3. Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions.
  4. Genetic association studies between dementia of the Alzheimer's type and three receptors for apolipoprotein E in a Caucasian population.
  5. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3.
  6. Absence of the A1252G mutation in alpha 1-antichymotrypsin in a North American population suffering from dementia.
  7. Regional HmPAO SPECT and CT measurements in the diagnosis of Alzheimer's disease.
  8. Hippocampus in delay eyeblink classical conditioning: essential for nefiracetam amelioration of learning in older rabbits.
  9. An ApoE-Abeta inhibition complex in Abeta fibril extension.
  10. Presence and treatment of vascular risk factors in patients with vascular cognitive impairment.
  11. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation.
  12. Does Alzheimer's disease start early in life?
  13. Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes.
  14. Presenilin-1 polymorphism in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia in Japanese population.
  15. Frontal lobe degeneration of non-Alzheimer type. Structural characteristics, diagnostic criteria and relation to other frontotemporal dementias.