All Comments by Benjamin Wolozin

  1. Alzheimer's disease. Bad for the heart, bad for the mind?
  2. The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner.
  3. Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p.
  4. Designing drugs to stop the formation of prion aggregates and other amyloids.
  5. Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type.
  6. Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells.
  7. Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain.
  8. On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells.
  9. Expression of apoptosis related proteins in brains of patients with Alzheimer's disease.
  10. Biochemical characterization of the core structure of alpha-synuclein filaments.
  11. Imaging brain amyloid of Alzheimer disease in vivo in transgenic mice with an Abeta peptide radiopharmaceutical.
  12. Tau-66: evidence for a novel tau conformation in Alzheimer's disease.
  13. A novel peptide prevents death in enriched neuronal cultures.
  14. ASP1 (BACE2) cleaves the amyloid precursor protein at the beta-secretase site.
  15. Distinct Ca2+ thresholds determine cytochrome c release or permeability transition pore opening in brain mitochondria.