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Weeding Mendel’s Garden: Can We Hoe Dubious Genetic Associations?

Scientists have uncovered hundreds of genetic variants that purportedly cause familial forms of various neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementias, and amyotrophic lateral sclerosis. But are all of these ...

Are Neurons Just Too Laissez-Faire about Repair?

Thierry Nouspikel led this live discussion on 14 July 2003. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Dr. Thierry Nouspikel led this live discussion on 14 July 2003. Moderated by Dr ...

The Pathogen Hypothesis

June Kinoshita, with Brian Balin, Denah Appelt, Joseph Lyons, Ruth Itzhaki, and Curtis Dobson, led this live discussion on 1 July 2004. Readers are invited to submit additional comments by using our Comments form at the bottom of the page.    Itzhaki RF, ...

Slow Aβ Clearance Is ApoE4’s Modus Operandi in Late-Onset AD

Alzforum has been pleased to partner with the journal Science Translational Medicine in hosting a Webinar discussion of a new Alzheimer’s disease research study published 29 June 2011. The journal generously granted free access to Castellano et al. for ...

ADCS Prevention Instrument Project

There is now a concerted push in the research community to find pharmacological and/or non-pharmacological interventions that can prevent or slow the progression of Alzheimer disease. But prevention trials promise to be long and potentially costly affairs ...

Mice on Trial? Issues in the Design of Drug Studies

Tiny and timid though it may be, the humble house mouse is not only one of the most successful mammalian species on Earth, but is also the dominant model organism for medical research, especially because of the ease with which it can be genetically ...

Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.

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