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APP Family: Clues to Function in Health and AD

The amyloid precursor protein was first cloned in 1987. Twenty years and 4,000+ papers later, the function of APP is still shrouded in mystery, despite the overwhelming weight of evidence linking the precursor protein to Alzheimer disease. Is the field ...

Resolving Controversies on the Path to AD Therapeutics

Alzforum was pleased to partner with the journals Nature Medicine and Nature Reviews Drug Discovery in hosting a Webinar panel discussion on Thursday, 29 September 2011. At issue were a Perspective article by Dennis Selkoe on "Resolving controversies ...

Neuroinflammation—A Prelude to Alzheimer's?

Neuroinflammation plays a major role in Alzheimer's disease, but whether it represents a cause or a response to pathology is unclear. In the November 27 Nature Reviews Neurology, Dimitrije Krstic and Irene Knuesel argue that age-related chronic ...

Cerebrometabolic Deficiency in Alzheimer's Disease

John P. Blass and Gary Gibson led this live discussion on 15 April 2002. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live discussion held 15 April 2002. Participants: John Blass, Gary ...

Differential Neuronal Vulnerability

Vikram Khurana and Ole Isacson led this live discussion on 29 June 2005. Readers are invited to submit additional comments by using our Comments form at the bottom of the page. Transcript: Live Discussion led by Ole Isacson and Vikram Khurana on 29 June ...

Have a topic idea for a webinar? We would love to hear it. Send an email to webinars [at] alzforum [dot] org.

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