Therapeutics

Breaking News

23 Dec 2014  Roche Axed its SCarletRoad trial of gantenerumab based on a planned futility analysis. The DIAN-TU trial of this antibody will continue.

This database provides a catalog of the therapeutics currently or previously tested as treatment for Alzheimer's disease and related disorders, focusing on those that have progressed to Phase 2 or beyond in U.S. clinical trials. We strive to keep this database up-to-date and welcome you to contact us at therapeutics@alzforum.org.

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AD Target / Therapy Types

The two tables below organize the therapeutics within this database by therapy type and proposed target type. The number of therapeutics within each category is indicated according to the highest phase each therapeutic has achieved in U.S. clinical trials. For example, if a given therapeutic is in both Phase 2 and Phase 3 trials, it is included in the Phase 3 total.

Further Reading

News

  1. Nanobubbles: Potent Potion, or Just Effervescence?
  2. New Treatments for Alzheimer’s Behavioral Symptoms on Horizon
  3. New Ideas for Alzheimer’s Treatment: What’s on Offer in 2014?
  4. End of the RoAD for Gantenerumab? Roche Declares Prodromal Alzheimer’s Trial Futile

Webinars

  1. Resolving Controversies on the Path to AD Therapeutics
  2. Treating Before Symptoms—ADCS Invites Ideas for Clinical Trials in Very Early AD
  3. Of Mice and Men: Bridging the Translational Disconnect in CNS Drug Discovery
  4. Can We (Should We?) Develop “Smart Drugs” to Stave Off Age-Related Memory Loss?

Other Resources

ADDF ACCESS is a program to provide scientists in academia and small biotechnology companies with access to a virtual network of drug discovery experts and contract research organizations (CROs) that have experience developing therapies for neurodegenerative diseases.

Patient Resources