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Name Synonyms FDA Status Company Target Type Therapy Type Condition Approved
For
ALZT-OP1 Cromolyn sodium, Intal,
Ibuprofen
3 AZTherapies, Inc. Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease
Azeliragon PF-04494700 ,
TTP488
3 Pfizer, TransTech Pharma, Inc., vTv Therapeutics LLC Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease
CHF 5074 2, Inactive CereSpir™ Incorporated, Chiesi Pharmaceuticals Inc. Amyloid-Related, Inflammation, Other Small Molecule Mild Cognitive Impairment, Alzheimer's Disease
Celecoxib Celebrex Discontinued Pfizer Inflammation Small Molecule Alzheimer's Disease Pain, Arthritis
Epigallocatechin Gallate (EGCG) Sunphenon EGCg 2/3, 2, 3 Taiyo International Amyloid-Related, Inflammation, Other Dietary Supplement Alzheimer's Disease, Down's Syndrome, Multiple System Atrophy
Etanercept Enbrel™ 2 Amgen, Inc., Pfizer Inflammation Immunotherapy (passive) Alzheimer's Disease Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondilysis
GC 021109 1 GliaCure Inflammation Small Molecule Alzheimer's Disease
Gammagard™ Intravenous Immunoglobulin,
IVIg
Discontinued Baxter Healthcare Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease Immunodeficiency conditions
Gamunex Intravenous Immunoglobulin,
Human Albumin Combined With Flebogamma
2/3 Grifols Biologicals Inc. Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease Immunodeficiency, chronic inflammatory demyelinating neuropathy
HF0220 Discontinued Newron Inflammation Small Molecule Alzheimer's Disease
Ibuprofen Advil™,
Nuprin™ ,
Motrin™
Discontinued Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease Pain and Fever
Lornoxicam Discontinued, Discontinued JSW Lifesciences Inflammation Small Molecule Alzheimer's Disease, Mild Cognitive Impairment Pain in US
Minocycline Solodyn,
Arestin,
Minocin,
Dynacin
2 Inflammation Small Molecule Alzheimer's Disease
Naproxen Aleve™,
Anaprox™,
Naprosyn™
Discontinued Procter & Gamble, Roche Inflammation Small Molecule Alzheimer's Disease Over-the-counter drug for reduction of pain, fever, inflammation, and stiffness.
Octagam®10% Intravenous Immunoglobulin,
NewGam
Inactive, Inactive Octapharma Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease, Mild Cognitive Impairment Immunodeficiency disorders
PQ912 2 Probiodrug AG Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease
Pioglitazone AD4833,
Actos®,
Glustin™,
Piozone®
3 Takeda Pharmaceutical Company, Zinfandel Pharmaceuticals Inc. Inflammation, Other Small Molecule Mild Cognitive Impairment Type 2 diabetes mellitus
Prednisone Discontinued Inflammation Small Molecule Alzheimer's Disease
Rofecoxib Vioxx™ Discontinued Merck Inflammation Small Molecule Alzheimer's Disease Withdrawn from market
Sargramostim Leukine®,
GM-CSF
2 Genzyme, Sanofi Inflammation, Other, Unknown Other Alzheimer's Disease Bone Marrow Stimulation
Thalidomide Thalomid® 2/3 Celgene Corporation Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease
VX-745 2 EIP Pharma, LLC Inflammation Small Molecule Alzheimer's Disease
Young Plasma 1, 1 Alkahest, Inc., Grifols Biologicals Inc. Inflammation, Other, Unknown Other Progressive Supranuclear Palsy, Alzheimer's Disease