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Name Synonyms FDA Status Company Target Type Therapy Type Condition Approved
For
Acitretin Soriatane ,
Neotigason,
RO 101670
2 Stiefel Laboratories, Inc. Amyloid-Related Small Molecule Alzheimer's Disease Psoriasis in US
Affitope AD02 2 AFFiRiS AG Amyloid-Related Immunotherapy (active) Alzheimer's Disease
Alzhemed™ Vivimind™,
Tramiprosate,
NC-531,
homotaurine,
3-APS
Inactive Neurochem, Inc. Amyloid-Related Dietary Supplement Alzheimer's Disease None
AN-1792 AIP 001 Discontinued Janssen, Pfizer Amyloid-Related Immunotherapy (active) Alzheimer's Disease None
Avagacestat BMS-708163 Discontinued Bristol-Myers Squibb Amyloid-Related Small Molecule Alzheimer's Disease
AZD3293 BACE1 inhibitor 1 AstraZeneca Amyloid-Related Small Molecule Alzheimer's Disease
BAN2401 2 Biogen Idec, Eisai Co., Ltd. Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
Bapineuzumab AAB-001 Discontinued Janssen, Pfizer Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
BIIB037 1 Biogen Idec Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
CAD106 2, 2 Novartis Pharmaceuticals Corporation Amyloid-Related Immunotherapy (active) Alzheimer's Disease, None
CHF 5074 2, Inactive CereSpir™ Incorporated, Chiesi Pharmaceuticals Inc. Amyloid-Related, Inflammation, Other Small Molecule Mild Cognitive Impairment, Alzheimer's Disease
Crenezumab MABT5102A ,
RG7412
2 Genentech Amyloid-Related Immunotherapy (passive) Alzheimer's Disease None
E2609 BACE1 inhibitor 1 Biogen Idec, Eisai Co., Ltd. Amyloid-Related Small Molecule Alzheimer's Disease
ELND005 AZD-103,
Scyllo-inositol,
cyclohexane-1,2,3,4,5,6-hexol
2 Elan Corporation, Speranza Therapeutics Amyloid-Related Small Molecule Alzheimer's Disease None
Epigallocatechin Gallate (EGCG) Sunphenon EGCg 2/3, 2, 3 Taiyo International Amyloid-Related, Inflammation, Other Dietary Supplement Alzheimer's Disease, Down Syndrome, Multiple System Atrophy
EVP-0962 EVP 0015962 2, 2 FORUM Pharmaceuticals Inc. (was EnVivo Pharmaceuticals) Amyloid-Related Small Molecule Alzheimer's Disease, Mild Cognitive Impairment
Flurizan™ tarenflurbil ,
r-flurbiprofen,
MPC-7869
Discontinued Myriad Genetics & Laboratories Amyloid-Related Small Molecule Alzheimer's Disease None
Gammagard™ Intravenous Immunoglobulin,
IVIg
Discontinued Baxter Healthcare Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease Immunodeficiency conditions
Gamunex Intravenous Immunoglobulin,
Human Albumin Combined With Flebogamma
2/3 Grifols Biologicals Inc. Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease Immunodeficiency, chronic inflammatory demyelinating neuropathy
Gantenerumab RO4909832,
RG1450
3 Chugai Pharmaceutical Co., Ltd., Hoffmann-La Roche Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
Levetiracetam Keppra 2, Discontinued GlaxoSmithKline (GSK), Otsuka Pharmaceutical Co., Ltd., UCB S.A. Amyloid-Related, Other Small Molecule Mild Cognitive Impairment, Parkinson's Disease Epilepsy and Partial Seizures in U.S., European Union, plus about 20 other countries
LY2886721 β-secretase inhibitor Discontinued, Discontinued Eli Lilly & Co. Amyloid-Related Small Molecule Alzheimer's Disease, Mild Cognitive Impairment
MK-8931 MK-8931-009 ,
β-secretase inhibitor
3 Merck Amyloid-Related Small Molecule Alzheimer's Disease
Nasal Insulin Detemir,
Levemir,
Humulin,
Novolin
2, 2, 2, 2 Amyloid-Related, Other Small Molecule, Other Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple System Atrophy Diabetes
NIC5-15 Pinitol,
D-Pinitol
2 Humanetics Pharmaceuticals Corporation Amyloid-Related, Other Small Molecule, Dietary Supplement Alzheimer's Disease
Octagam® Intravenous Immunoglobulin,
NewGam
2, 2 Octapharma Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease, Mild Cognitive Impairment
PBT2 PBT-2 2, 2 Prana Biotechnology Limited Amyloid-Related, Metals Small Molecule Alzheimer's Disease, Huntington's Disease
Ponezumab PF-04360365 Discontinued, 2 Pfizer Amyloid-Related Immunotherapy (passive) Alzheimer's Disease, Cerebral Amyloid Angiopathy None
RG7129 RO5508887,
BACE1 Inhibitor
Discontinued Roche Amyloid-Related Small Molecule Alzheimer's Disease
SAR228810 1 Sanofi Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
Semagacestat LY450139 Dihydrate ,
hydroxylvaleryl monobenzocaprolactam
Discontinued Eli Lilly & Co. Amyloid-Related Small Molecule Alzheimer's Disease None
Solanezumab LY2062430 3 Eli Lilly & Co. Amyloid-Related Immunotherapy (passive) Alzheimer's Disease None
Thalidomide Thalomid® 2/3 Celgene Corporation Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease
TTP488 PF-04494700 ,
RAGE Inhibitor
Inactive Pfizer, TransTech Pharma, Inc. Amyloid-Related Small Molecule Alzheimer's Disease
Vanutide cridificar ACC-001,
PF-05236806
Discontinued Pfizer Amyloid-Related Immunotherapy (active) Alzheimer's Disease None