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Name Synonyms FDA Status Company Target Type Therapy Type Condition Approved
For
Acitretin Soriatane , Neotigason, RO 101670 2 Stiefel Laboratories, Inc. APP and Amyloid-Related Small Molecule Alzheimer's Disease Psoriasis in US
Affitope AD02 2 AFFiRiS AG, GlaxoSmithKline (GSK) APP and Amyloid-Related Immunotherapy (active) Alzheimer's Disease
Alzhemed™ Vivimind™, Tramiprosate, NC-531, homotaurine, 3-APS Inactive Neurochem, Inc. APP and Amyloid-Related Dietary Supplement Alzheimer's Disease None
AN-1792 AIP 001 Discontinued Janssen, Pfizer APP and Amyloid-Related Immunotherapy (active) Alzheimer's Disease None
Avagacestat BMS-708163 Discontinued Bristol-Myers Squibb APP and Amyloid-Related Small Molecule Alzheimer's Disease
AZD3293 BACE1 inhibitor 1 AstraZeneca APP and Amyloid-Related Small Molecule Alzheimer's Disease
BAN2401 2 Biogen Idec, Eisai Co., Ltd. APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
Bapineuzumab AAB-001 Discontinued Janssen, Pfizer APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
BIIB037 1 Biogen Idec APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
CAD106 2, 2 Novartis Pharmaceuticals Corporation APP and Amyloid-Related Immunotherapy (active) Alzheimer's Disease, None
CHF 5074 2, Inactive CereSpir™ Incorporated, Chiesi Pharmaceuticals Inc. APP and Amyloid-Related, Inflammation, Other Small Molecule Mild Cognitive Impairment, Alzheimer's Disease
Crenezumab MABT5102A , RG7412 2 Genentech APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease None
E2609 BACE1 inhibitor 1 Biogen Idec, Eisai Co., Ltd. APP and Amyloid-Related Small Molecule Alzheimer's Disease
ELND005 AZD-103, Scyllo-inositol, cyclohexane-1,2,3,4,5,6-hexol 2 Elan Corporation, Speranza Therapeutics APP and Amyloid-Related Small Molecule Alzheimer's Disease None
EVP-0962 EVP 0015962 2, 2 FORUM Pharmaceuticals Inc. (was EnVivo Pharmaceuticals) APP and Amyloid-Related Small Molecule Alzheimer's Disease, Mild Cognitive Impairment
Flurizan™ tarenflurbil , r-flurbiprofen, MPC-7869 Discontinued Myriad Genetics & Laboratories APP and Amyloid-Related Small Molecule Alzheimer's Disease None
Gammagard™ Intravenous Immunoglobulin, IVIg Discontinued Baxter Healthcare APP and Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease Immunodeficiency conditions
Gamunex Intravenous Immunoglobulin, Human Albumin Combined With Flebogamma 2/3 Grifols Biologicals Inc. APP and Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease Immunodeficiency, chronic inflammatory demyelinating neuropathy
Gantenerumab RO4909832, RG1450 3 Chugai Pharmaceutical Co., Ltd., Hoffmann-La Roche APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
Levetiracetam Keppra 2, Discontinued GlaxoSmithKline (GSK), Otsuka Pharmaceutical Co., Ltd., UCB S.A. APP and Amyloid-Related, Other Small Molecule Mild Cognitive Impairment, Parkinson's Disease Epilepsy and Partial Seizures in U.S., European Union, plus about 20 other countries
LY2886721 β-secretase inhibitor Discontinued, Discontinued Eli Lilly & Co. APP and Amyloid-Related Small Molecule Alzheimer's Disease, Mild Cognitive Impairment
MK-8931 MK-8931-009 , β-secretase inhibitor 3 Merck APP and Amyloid-Related Small Molecule Alzheimer's Disease
NIC5-15 Pinitol, D-Pinitol 2 Humanetics Pharmaceuticals Corporation APP and Amyloid-Related, Other Small Molecule, Dietary Supplement Alzheimer's Disease
Octagam® Intravenous Immunoglobulin, NewGam 2, 2 Octapharma APP and Amyloid-Related, Inflammation Immunotherapy (passive) Alzheimer's Disease, Mild Cognitive Impairment
PBT2 2, 2 Prana Biotechnology Limited APP and Amyloid-Related, Metals Small Molecule Alzheimer's Disease, Huntington's Disease
Ponezumab PF-04360365 Discontinued, 2 Pfizer APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease, Cerebral Amyloid Angiopathy None
RG7129 RO5508887, BACE1 Inhibitor Discontinued Roche Products (Ireland) Limited APP and Amyloid-Related Small Molecule Alzheimer's Disease
SAR228810 1 Sanofi APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease
Semagacestat LY450139 Dihydrate , hydroxylvaleryl monobenzocaprolactam Discontinued Eli Lilly & Co. APP and Amyloid-Related Small Molecule Alzheimer's Disease None
Solanezumab LY2062430 3 Eli Lilly & Co. APP and Amyloid-Related Immunotherapy (passive) Alzheimer's Disease None
Thalidomide Thalomid® 2/3 Celgene Corporation APP and Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease
TTP488 PF-04494700 , RAGE Inhibitor Inactive Pfizer, TransTech Pharma, Inc. APP and Amyloid-Related Small Molecule Alzheimer's Disease
Vanutide cridificar ACC-001, PF-05236806 Discontinued Pfizer APP and Amyloid-Related Immunotherapy (active) Alzheimer's Disease None