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Name Synonyms FDA Status Company Target Type Therapy Type Condition Approved
For
ABT-126 2 AbbVie Cholinergic System Small Molecule Alzheimer's Disease
Acitretin Soriatane , Neotigason, RO 101670 2 Stiefel Laboratories, Inc. APP and Amyloid-Related Small Molecule Alzheimer's Disease Psoriasis in US
Bexarotene Targretin® 2 Unknown Small Molecule Mild Cognitive Impairment Cutaneous T-cell Lymphoma in US
Circadin 2 Neurim Pharmaceuticals Ltd. Other Small Molecule Alzheimer's Disease Insomnia in US
EHT 0202 Etazolate 2 ExonHit Therapeutics Other Small Molecule Alzheimer's Disease None
ELND005 AZD-103, Scyllo-inositol, cyclohexane-1,2,3,4,5,6-hexol 2 Elan Corporation, Speranza Therapeutics APP and Amyloid-Related Small Molecule Alzheimer's Disease None
EVP-0962 EVP 0015962 2, 2 FORUM Pharmaceuticals Inc. (was EnVivo Pharmaceuticals) APP and Amyloid-Related Small Molecule Alzheimer's Disease, Mild Cognitive Impairment
Exendin-4 Exenatide, Byetta, Bydureon 2 Other Small Molecule Alzheimer's Disease Diabetes mellitus in US
G-CSF Filgrastim 2 Other Small Molecule Alzheimer's Disease Neutropenia in US
Ladostigil Hemitartrate TV-3,326 2 Avraham Pharmaceuticals Ltd Cholinergic System Small Molecule Mild Cognitive Impairment
Levetiracetam Keppra 2, Discontinued GlaxoSmithKline (GSK), Otsuka Pharmaceutical Co., Ltd., UCB S.A. APP and Amyloid-Related, Other Small Molecule Mild Cognitive Impairment, Parkinson's Disease Epilepsy and Partial Seizures in U.S., European Union, plus about 20 other countries
Liraglutide Victoza™ 2 Novo Nordisk A/S Other Small Molecule Alzheimer's Disease
Minocycline Solodyn, Arestin, Minocin, Dynacin 2 Inflammation Small Molecule Alzheimer's Disease
MK-7622 2 Merck Unknown Small Molecule Alzheimer's Disease
MSDC-0160 Mitoglitazone 2 Metabolic Solutions Development Company Other Small Molecule Alzheimer's Disease
NIC5-15 Pinitol, D-Pinitol 2 Humanetics Pharmaceuticals Corporation APP and Amyloid-Related, Other Small Molecule, Dietary Supplement Alzheimer's Disease
Nicotinamide Enduramide, Niacinamide, Nicotinic acid amide, Vitamin B3 2 Other Small Molecule Alzheimer's Disease
ORM-12741 2 Orion Pharma Other Neurotransmitter Systems Small Molecule Alzheimer's Disease
PBT2 2, 2 Prana Biotechnology Limited APP and Amyloid-Related, Metals Small Molecule Alzheimer's Disease, Huntington's Disease
PF-05212377 PF-5212377, WYE-103760, SAM-760 2 Pfizer Other Neurotransmitter Systems Small Molecule Alzheimer's Disease
R-pramipexole RPPX, Dexpramipexole, KNS-760704 , BIIB 050 2, Discontinued Biogen Idec, Knopp Biosciences LLC, Virginia Commonwealth University Other Neurotransmitter Systems, Other Small Molecule Alzheimer's Disease, Amyotrophic Lateral Sclerosis
Rilapladib SB-659032 2 GlaxoSmithKline (GSK) Other Small Molecule Alzheimer's Disease
Riluzole Rilutek®, RP 54274 2, Discontinued, Approved, Discontinued Sanofi Other Neurotransmitter Systems, Other Small Molecule Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Huntington's Disease Amyotrophic Lateral Sclerosis in many countries
SAR110894D 2 Sanofi Other Small Molecule Alzheimer's Disease
T-817MA 2 Toyama Chemical Co., Ltd. Unknown Small Molecule Alzheimer's Disease