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Name Synonyms FDA Status Company Target Type Therapy Type Condition Approved
For
AGB101 Levetiracetam,
Keppra
2, Discontinued AgeneBio, Inc. Amyloid-Related, Other Small Molecule Mild Cognitive Impairment, Parkinson's Disease Epilepsy and Partial Seizures in U.S., European Union, plus about 20 other countries
Acitretin Soriatane ,
Neotigason,
RO 101670
2 Actavis, Allergan plc Amyloid-Related Small Molecule Alzheimer's Disease Psoriasis in US
Anavex 2-73 2 Anavex Life Science Corp. Other Small Molecule Alzheimer's Disease
BI 409306 SUB 166499 2 Boehringer Ingelheim Other Neurotransmitters, Other Small Molecule Alzheimer's Disease
Bexarotene Targretin® 2 Ligand Pharmaceuticals, Inc., ReXceptor Inc. Amyloid-Related, Unknown Small Molecule Alzheimer's Disease Cutaneous T-cell Lymphoma in US
Circadin 2 Neurim Pharmaceuticals Ltd. Other Small Molecule Alzheimer's Disease Insomnia
Dexpramipexole R-pramipexole,
RPPX,
KNS-760704 ,
BIIB 050
2, Discontinued Biogen, Knopp Biosciences LLC, Virginia Commonwealth University Other Neurotransmitters, Other Small Molecule Alzheimer's Disease, Amyotrophic Lateral Sclerosis
E2609 BACE inhibitor 2 Biogen, Eisai Co., Ltd. Amyloid-Related Small Molecule Alzheimer's Disease
EHT 0202 Etazolate 2 ExonHit Therapeutics Other Small Molecule Alzheimer's Disease None
ELND005 AZD-103,
Scyllo-inositol,
cyclohexane-1,2,3,4,5,6-hexol
2 Elan Corporation, Speranza Therapeutics, Transition Therapeutics, Inc. Amyloid-Related Small Molecule Alzheimer's Disease None
EVP-0962 EVP 0015962 2, 2 FORUM Pharmaceuticals Inc. Amyloid-Related Small Molecule Alzheimer's Disease, Mild Cognitive Impairment
Exendin-4 Exenatide,
Byetta,
Bydureon
2 Other Small Molecule Alzheimer's Disease Diabetes mellitus in US
G-CSF Filgrastim 2 Other Small Molecule Alzheimer's Disease Neutropenia in US
Ladostigil Hemitartrate TV-3,326 2 Avraham Pharmaceuticals Ltd Cholinergic System Small Molecule Mild Cognitive Impairment
Liraglutide Victoza™ 2 Novo Nordisk A/S Other Small Molecule Alzheimer's Disease
MK-7622 2 Merck Unknown Small Molecule Alzheimer's Disease
MSDC-0160 Mitoglitazone 2 Metabolic Solutions Development Company Other Small Molecule Alzheimer's Disease
Minocycline Solodyn,
Arestin,
Minocin,
Dynacin
2 Inflammation Small Molecule Alzheimer's Disease
NIC5-15 Pinitol,
D-Pinitol
2 Humanetics Pharmaceuticals Corporation Amyloid-Related, Other Small Molecule, Dietary Supplement Alzheimer's Disease
Nasal Insulin Detemir,
Levemir,
Humulin,
Novolin
2, 2, 2, 2 Amyloid-Related, Other Small Molecule, Other Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple System Atrophy Diabetes
Nicotinamide Enduramide,
Niacinamide,
Nicotinic acid amide,
Vitamin B3
2 Other Small Molecule Alzheimer's Disease
ORM-12741 2 Orion Pharma Other Neurotransmitters Small Molecule Alzheimer's Disease
PBT2 PBT-2 2, 2 Prana Biotechnology Limited Amyloid-Related, Metals Small Molecule Alzheimer's Disease, Huntington's Disease
PQ912 2 Probiodrug AG Amyloid-Related, Inflammation Small Molecule Alzheimer's Disease
RVT-101 SB-742457 ,
GSK 742457
2, 2 Axovant Sciences Ltd. Other Neurotransmitters Small Molecule Alzheimer's Disease, Dementia
Rilapladib SB-659032 2 GlaxoSmithKline (GSK) Other Small Molecule Alzheimer's Disease
Riluzole Rilutek®,
RP 54274
2, Discontinued, Approved, Discontinued Sanofi Other Neurotransmitters, Other Small Molecule Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Huntington's Disease Amyotrophic Lateral Sclerosis in many countries
SAR110894D 2 Sanofi Other Small Molecule Alzheimer's Disease
SUVN-502 2 Suven Life Sciences Ltd Other Neurotransmitters Small Molecule Alzheimer's Disease
Saracatinib AZD0530 2 AstraZeneca Other Small Molecule Alzheimer's Disease
T-817MA T 817MA, T817MA 2 Toyama Chemical Co., Ltd. Other, Unknown Small Molecule Alzheimer's Disease
T3D-959 DB959 2 T3D Therapeutics, Inc. Other Small Molecule Alzheimer's Disease
VX-745 2 EIP Pharma, LLC Inflammation Small Molecule Alzheimer's Disease