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Name Synonyms FDA Status Company Target Type Therapy Type Condition Approved
For
AVP-923 Nuedexta,
Zenvia
2, 3, 3 Avanir Pharmaceuticals Other Neurotransmitters Small Molecule Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Parkinson's Disease
ORM-12741 2 Orion Pharma Other Neurotransmitters Small Molecule Alzheimer's Disease
PF-05212377 PF-5212377,
WYE-103760,
SAM-760
2 Pfizer Other Neurotransmitters Small Molecule Alzheimer's Disease
R-pramipexole RPPX,
Dexpramipexole,
KNS-760704 ,
BIIB 050
2, Discontinued Biogen Idec, Knopp Biosciences LLC, Virginia Commonwealth University Other Neurotransmitters, Other Small Molecule Alzheimer's Disease, Amyotrophic Lateral Sclerosis
RG1577 RO4602522 2 Evotech AG, Roche Other Neurotransmitters, Other Small Molecule Alzheimer's Disease
Riluzole Rilutek®,
RP 54274
2, Discontinued, Approved, Discontinued Sanofi Other Neurotransmitters, Other Small Molecule Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Huntington's Disease Amyotrophic Lateral Sclerosis in many countries