Therapeutics
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| Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
|---|---|---|---|---|---|---|
| ABBV-916 | N3pG-Abeta mAb | Alzheimer's Disease (Phase 2) | Amyloid-Related | Immunotherapy (passive) | ||
| ABvac40 | Alzheimer's Disease (Phase 2) | Araclon Biotech | Amyloid-Related | Immunotherapy (active) | ||
| ACI-24 | ACI-24.060, Pal1-15 acetate salt |
Alzheimer's Disease (Phase 2), Down's Syndrome (Phase 2) | AC Immune SA | Amyloid-Related | Immunotherapy (active) | |
| Acitretin | Soriatane , Neotigason, RO 101670 |
Alzheimer's Disease (Phase 2) | Actavis, Allergan plc | Amyloid-Related | Small Molecule | Psoriasis in US |
| Bexarotene | Targretin® | Alzheimer's Disease (Phase 2) | Ligand Pharmaceuticals, Inc., ReXceptor Inc. | Amyloid-Related, Unknown | Small Molecule | Cutaneous T-cell Lymphoma in US |
| Buntanetap | Posiphen, ANVS-401, Posiphen tartrate |
Alzheimer's Disease (Phase 2), Parkinson's Disease (Phase 1/2) | Annovis Bio | Amyloid-Related, alpha-synuclein | Small Molecule | |
| CT1812 | Elayta | Alzheimer's Disease (Phase 2) | Cognition Therapeutics Inc. | Amyloid-Related | Small Molecule | |
| Lenalidomide | Revlimid | Alzheimer's Disease (Phase 2) | Celgene Corporation | Amyloid-Related, Inflammation | Small Molecule | Multiple myeloma, lymphoma, myelodysplastic syndromes |
| Levetiracetam | Keppra | Alzheimer's Disease (Phase 2), Parkinson's Disease (Discontinued) | UCB S.A. | Amyloid-Related, Other | Small Molecule | Epilepsy and Partial Seizures in U.S., European Union, plus about 20 other countries |
| Nasal Insulin | Detemir, Levemir, Humulin, Novolin, glulisine |
Alzheimer's Disease (Phase 2/3), Mild Cognitive Impairment (Phase 2), Parkinson's Disease (Phase 2), Multiple System Atrophy (Phase 2) | Amyloid-Related, Other | Small Molecule, Other | Diabetes | |
| NIC5-15 | Pinitol, D-Pinitol |
Alzheimer's Disease (Phase 2) | Humanetics Pharmaceuticals Corporation | Amyloid-Related, Other | Small Molecule, Supplement, Dietary | |
| UB-311 | Alzheimer's Disease (Phase 2) | United Neuroscience, Vaxxinity | Amyloid-Related | Immunotherapy (active) | ||
| Varoglutamstat | PQ912 | Alzheimer's Disease (Phase 2) | Probiodrug AG, Vivoryon Therapeutics N.V. | Amyloid-Related, Inflammation | Small Molecule |