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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
AGB101 Levetiracetam,
Keppra
Mild Cognitive Impairment (Phase 3), Parkinson's Disease (Discontinued) AgeneBio, Inc. Amyloid-Related, Other Small Molecule Epilepsy and Partial Seizures in U.S., European Union, plus about 20 other countries
ALZT-OP1 Cromolyn sodium, Intal,
Ibuprofen
Alzheimer's Disease (Phase 3) AZTherapies, Inc. Amyloid-Related, Inflammation Small Molecule
AZD3293 LY3314814,
BACE inhibitor
Alzheimer's Disease (Phase 3) AstraZeneca, Eli Lilly & Co. Amyloid-Related Small Molecule
Aducanumab BIIB037 Alzheimer's Disease (Phase 3) Biogen Amyloid-Related Immunotherapy (passive)
Azeliragon PF-04494700 ,
TTP488
Alzheimer's Disease (Phase 3) Pfizer, TransTech Pharma, Inc., vTv Therapeutics LLC Amyloid-Related, Inflammation Small Molecule
Crenezumab MABT5102A ,
RG7412
Alzheimer's Disease (Phase 3) AC Immune SA, Genentech, Hoffmann-La Roche Amyloid-Related Immunotherapy (passive) None
Elenbecestat E2609,
BACE inhibitor
Alzheimer's Disease (Phase 3) Biogen, Eisai Co., Ltd. Amyloid-Related Small Molecule
Gantenerumab RO4909832,
RG1450
Alzheimer's Disease (Phase 3) Chugai Pharmaceutical Co., Ltd., Hoffmann-La Roche Amyloid-Related Immunotherapy (passive)
Solanezumab LY2062430 Alzheimer's Disease (Phase 3) Eli Lilly & Co. Amyloid-Related Immunotherapy (passive) None
Verubecestat MK-8931, MK-8931-009 ,
BACE inhibitor
Alzheimer's Disease (Phase 3) Merck Amyloid-Related Small Molecule