Therapeutics
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| Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Condition | Approved For |
|---|---|---|---|---|---|---|---|
| Neflamapomid | VX-745 | 2 | EIP Pharma, LLC | Inflammation | Small Molecule | Alzheimer's Disease | |
| Acitretin | Soriatane , Neotigason, RO 101670 |
2 | Actavis, Allergan plc | Amyloid-Related | Small Molecule | Alzheimer's Disease | Psoriasis in US |
| Anavex 2-73 | 2 | Anavex Life Science Corp. | Other | Small Molecule | Alzheimer's Disease | ||
| BI 409306 | SUB 166499 | 2 | Boehringer Ingelheim | Other Neurotransmitters, Other | Small Molecule | Alzheimer's Disease | |
| Bexarotene | Targretin® | 2 | Ligand Pharmaceuticals, Inc., ReXceptor Inc. | Amyloid-Related, Unknown | Small Molecule | Alzheimer's Disease | Cutaneous T-cell Lymphoma in US |
| Circadin | 2 | Neurim Pharmaceuticals Ltd. | Other | Small Molecule | Alzheimer's Disease | Insomnia | |
| Dexpramipexole | R-pramipexole, RPPX, KNS-760704 , BIIB 050 |
2, Discontinued | Biogen, Knopp Biosciences LLC, Virginia Commonwealth University | Other Neurotransmitters, Other | Small Molecule | Alzheimer's Disease, Amyotrophic Lateral Sclerosis | |
| EHT 0202 | Etazolate | 2 | ExonHit Therapeutics | Other | Small Molecule | Alzheimer's Disease | None |
| ELND005 | AZD-103, Scyllo-inositol, cyclohexane-1,2,3,4,5,6-hexol |
2 | Elan Corporation, Speranza Therapeutics, Transition Therapeutics, Inc. | Amyloid-Related | Small Molecule | Alzheimer's Disease | None |
| EVP-0962 | EVP 0015962 | 2, 2 | FORUM Pharmaceuticals Inc. | Amyloid-Related | Small Molecule | Alzheimer's Disease, Mild Cognitive Impairment | |
| Exendin-4 | Exenatide, Byetta, Bydureon |
2 | Other | Small Molecule | Alzheimer's Disease | Diabetes mellitus in US | |
| G-CSF | Filgrastim | 2 | Other | Small Molecule | Alzheimer's Disease | Neutropenia in US | |
| LY3202626 | BACE Inhibitor | 2 | Eli Lilly & Co. | Amyloid-Related | Small Molecule | Alzheimer's Disease | |
| Liraglutide | Victoza™ | 2 | Novo Nordisk A/S | Other | Small Molecule | Alzheimer's Disease | |
| MSDC-0160 | Mitoglitazone | 2 | Metabolic Solutions Development Company | Other | Small Molecule | Alzheimer's Disease | |
| Minocycline | Solodyn, Arestin, Minocin, Dynacin |
2 | Inflammation | Small Molecule | Alzheimer's Disease | ||
| NIC5-15 | Pinitol, D-Pinitol |
2 | Humanetics Pharmaceuticals Corporation | Amyloid-Related, Other | Small Molecule, Dietary Supplement | Alzheimer's Disease | |
| Nasal Insulin | Detemir, Levemir, Humulin, Novolin |
2/3, 2, 2, 2 | Amyloid-Related, Other | Small Molecule, Other | Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, Multiple System Atrophy | Diabetes | |
| Nicotinamide | Enduramide, Niacinamide, Nicotinic acid amide, Vitamin B3 |
2 | Other | Small Molecule | Alzheimer's Disease | ||
| ORM-12741 | 2 | Orion Pharma | Other Neurotransmitters | Small Molecule | Alzheimer's Disease | ||
| PBT2 | PBT-2 | 2, 2 | Prana Biotechnology Limited | Amyloid-Related, Metals | Small Molecule | Alzheimer's Disease, Huntington's Disease | |
| PQ912 | 2 | Probiodrug AG | Amyloid-Related, Inflammation | Small Molecule | Alzheimer's Disease | ||
| PXT864 | PXT00864 | 2 | Pharnext | Other Neurotransmitters | Small Molecule | Alzheimer's Disease | |
| Pimavanserin | Nuplazid, ACP-103, Pimavanserin tartrate |
2, 3 | Acadia Pharmaceuticals | Other Neurotransmitters | Small Molecule | Alzheimer's Disease, Schizophrenia | Parkinson's psychosis |
| Piromelatine | Neu-P11 | 2 | Neurim Pharmaceuticals Ltd. | Other Neurotransmitters, Other | Small Molecule | Alzheimer's Disease | |
| Rilapladib | SB-659032 | 2 | GlaxoSmithKline (GSK) | Other | Small Molecule | Alzheimer's Disease | |
| Riluzole | Rilutek®, RP 54274 |
2, Discontinued, Approved, Discontinued | Sanofi | Other Neurotransmitters, Other | Small Molecule | Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Huntington's Disease | Amyotrophic Lateral Sclerosis in many countries |
| S47445 | CX1632 | 2 | Cortex Pharmaceuticals, Inc., Servier | Other Neurotransmitters | Small Molecule | Alzheimer's Disease | |
| SAR110894D | 2 | Sanofi | Other | Small Molecule | Alzheimer's Disease | ||
| SUVN-502 | 2 | Suven Life Sciences Ltd | Other Neurotransmitters | Small Molecule | Alzheimer's Disease | ||
| Saracatinib | AZD0530 | 2 | AstraZeneca | Other | Small Molecule | Alzheimer's Disease | |
| T-817MA | T 817MA, T817MA | 2 | Toyama Chemical Co., Ltd. | Other, Unknown | Small Molecule | Alzheimer's Disease | |
| T3D-959 | DB959 | 2 | T3D Therapeutics, Inc. | Other | Small Molecule | Alzheimer's Disease | |
| Telmisartan | Micardis | 2 | Boehringer Ingelheim | Other | Small Molecule | Alzheimer's Disease | Hypertension |
| XanamemTM | UE 2343 | 2 | Actinogen Medical | Other | Small Molecule | Alzheimer's Disease |