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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
Anavex 2-73 Alzheimer's Disease (Phase 2) Anavex Life Science Corp. Other Small Molecule
BI 409306 SUB 166499 Alzheimer's Disease (Phase 2) Boehringer Ingelheim Other Neurotransmitters, Other Small Molecule
Cerebrolysin Alzheimer's Disease (Phase 2) Ebewe Pharmaceutical Other Other
Circadin Alzheimer's Disease (Phase 2) Neurim Pharmaceuticals Ltd. Other Small Molecule Insomnia
Curcumin diferuloylmethane,
Longvida™
Alzheimer's Disease (Phase 2) Verdure Sciences Other, Unknown Dietary Supplement None
Dexpramipexole R-pramipexole,
RPPX,
KNS-760704 ,
BIIB 050
Alzheimer's Disease (Phase 2), Amyotrophic Lateral Sclerosis (Discontinued) Biogen, Knopp Biosciences LLC, Virginia Commonwealth University Other Neurotransmitters, Other Small Molecule
EHT 0202 Etazolate Alzheimer's Disease (Phase 2) ExonHit Therapeutics Other Small Molecule None
Edonerpic T-817 MA, T 817 Alzheimer's Disease (Phase 2) Toyama Chemical Co., Ltd. Other, Unknown Small Molecule
Exendin-4 Exenatide,
Byetta,
Bydureon
Alzheimer's Disease (Phase 2) Other Small Molecule Diabetes mellitus in US
G-CSF Filgrastim Alzheimer's Disease (Phase 2) Other Small Molecule Neutropenia in US
Liraglutide Victoza™ Alzheimer's Disease (Phase 2) Novo Nordisk A/S Other Small Molecule
MSDC-0160 Mitoglitazone Alzheimer's Disease (Phase 2) Metabolic Solutions Development Company Other Small Molecule
Melatonin Alzheimer's Disease (Phase 2) Other Dietary Supplement None
NIC5-15 Pinitol,
D-Pinitol
Alzheimer's Disease (Phase 2) Humanetics Pharmaceuticals Corporation Amyloid-Related, Other Small Molecule, Dietary Supplement
Nasal Insulin Detemir,
Levemir,
Humulin,
Novolin
Alzheimer's Disease (Phase 2/3), Mild Cognitive Impairment (Phase 2), Parkinson's Disease (Phase 2), Multiple System Atrophy (Phase 2) Amyloid-Related, Other Small Molecule, Other Diabetes
Nicotinamide Enduramide,
Niacinamide,
Nicotinic acid amide,
Vitamin B3
Alzheimer's Disease (Phase 2) Other Small Molecule
Piromelatine Neu-P11 Alzheimer's Disease (Phase 2) Neurim Pharmaceuticals Ltd. Other Neurotransmitters, Other Small Molecule
Repetitive Transcranial Magnetic Stimulation rTMS Alzheimer's Disease (Phase 2) Neuronix Ltd Other Procedural Intervention
Rilapladib SB-659032 Alzheimer's Disease (Phase 2) GlaxoSmithKline (GSK) Other Small Molecule
Riluzole Rilutek®,
RP 54274
Alzheimer's Disease (Phase 2), Parkinson's Disease (Discontinued), Amyotrophic Lateral Sclerosis (Approved), Huntington's Disease (Discontinued) Sanofi Other Neurotransmitters, Other Small Molecule Amyotrophic Lateral Sclerosis in many countries
SAR110894D Alzheimer's Disease (Phase 2) Sanofi Other Small Molecule
Saracatinib AZD0530 Alzheimer's Disease (Phase 2) AstraZeneca Other Small Molecule
Sargramostim Leukine®,
GM-CSF
Alzheimer's Disease (Phase 2) Genzyme, Sanofi Inflammation, Other, Unknown Other Bone Marrow Stimulation
T3D-959 DB959 Alzheimer's Disease (Phase 2) T3D Therapeutics, Inc. Other Small Molecule
Telmisartan Micardis Alzheimer's Disease (Phase 2) Boehringer Ingelheim Other Small Molecule Hypertension
XanamemTM UE 2343 Alzheimer's Disease (Phase 2) Actinogen Medical Other Small Molecule